What Are the Symptoms of Pellagra?
Pellagra, also known as rickets, is a vitamin-deficient disease. The main causes are a lack of vitamin B3 (nicotinic acid) and proteins, especially those that contain the essential amino acid tryptophan. Tryptophan can be converted into nicotinic acid, and about 60mg of tryptophan can be converted into 1mg of niacin, which requires the participation of vitamins B1, B2, and B6. Therefore, foods rich in tryptophan but not containing niacin, such as milk, can also effectively prevent pellagra. However, if all tryptophan ingested through food is used for protein synthesis, it may still cause pellagra.
pellagra
discuss
- Chinese name
- Pellagra
- Foreign name
- pellagra
- Category
- Disease name
- Subject
- medicine
- Influencing factors
- Vitamin B
- Features
- dermatitis
- Diagnosis
- Erythema after sun exposure, etc.
- Treatment
- Oral niacin
- Pellagra, also known as rickets, is a vitamin-deficient disease. The main causes are a lack of vitamin B3 (nicotinic acid) and proteins, especially those that contain the essential amino acid tryptophan. Tryptophan can be converted into nicotinic acid, and about 60mg of tryptophan can be converted into 1mg of niacin, which requires the participation of vitamins B1, B2, and B6. Therefore, foods rich in tryptophan but not containing niacin, such as milk, can also effectively prevent pellagra. However, if all tryptophan ingested through food is used for protein synthesis, it may still cause pellagra.
- Pellagra is a regional epidemic that occurs mainly in Africa, Mexico, Indonesia, and China. In export-oriented societies, people with pellagra are generally poor, alcoholic homeless people or people with mental illness who refuse to eat.
- Tryptophan is an essential amino acid and is abundant in soy, meat, poultry, fish, and eggs. It is unclear whether there is a certain relationship between leucine and pellagra. [1]
- Caused by vitamin B deficiency, clinically characterized by dermatitis, intestinal and neuropsychiatric symptoms. Diagnosis points: 1. After exposure to the sun, bright red and purple spots appear on the exposed area, swelling, exudation, redness at the edges, clear state, long-term hypertrophy, rough, tan, may be accompanied by stomatitis, glossitis, beef-like tongue, See Figure 2. 2. Gastrointestinal symptoms include nausea, vomiting, and diarrhea. 3. Insomnia, anxiety, depression, and other neurological symptoms, peripheral neuritis, such as limb numbness, burning, and pain. 4. Blood niacin is below normal. Treatment points: 1. Treat primary gastrointestinal diseases and remove incentives. 2. Oral niacin 50-100mg / times, 3 times a day. 3. Eat animal protein and fresh green vegetables. 4. Protect from sun and external light-proofing agents. 5. Strengthen supportive care.