What are the symptoms of porphyria?

Porphyria is the name given by a group of rare disorders in which there are shortcomings of the enzymes needed to produce the hem of the substance. HEME is a red colored pigment made in the liver and bone marrow, which is part of hemoglobin in red blood cells. Porphyria can affect the skin, nervous system or both. Symptoms of porphyria affecting the skin develop in response to sunlight and may include itching, blister and swelling. When porphyria affects the nervous system, psychiatric symptoms may occur as well as abdominal pain, nausea and vomiting and muscle weakness or paralysis. In every significant type of porphyria there is a lack of another of the eight enzymes used in the hem production process. The deficiency in the HEMU production route leads to the accumulation of substances used in the production process and, as these substances accumulate in the body, develop symptoms of porphyria.

porphyria cutanea tarda is a type of porphyrie that isIt occurs most often, usually in men over 50 years of age. It may develop as a result of alcohol abuse, chemical exposure or in conjunction with certain drugs such as contraception. Symptoms of porphyria cutanea Tarda occur when the skin is exposed to sunlight. The skin turns red and it can develop itching and large blisters, along with abnormal hair growth and skin pigmentation. Iron can occur in the body and liver damage may occur.

Acute intermittent porphyria is the most common porphyria affecting the nervous system. Here the symptoms of porphyria are extremely variable and some people have no symptoms at all. A severe attack can begin with the restlessness of the abdominal pain, perhaps with constipation and vomiting. Urine may seem red or dark, to remove accumulated substances that are part of the heme production process.

Psychiatric problems such as hallucinations, depression or mania may also be symptoms of acute intermittent porphyria. Different muscles can be weak orEven paralyzed and in extreme cases could be difficult to breathe. The armor or numbness of the limbs could develop and one can have seizures or confused. Death could suddenly occur due to irregular heart rhythm.

Porphyria control varies according to the type and severity of the attack. Well -known causes avoid if possible, and symptoms of porphyria are sometimes treated with drugs or by heme in a vein. In the hospital, serious episodes are usually governed and in some cases bone marrow or liver transplantation can be carried out.