What causes disappearing white mass?
The disappearance of white matter (VWM) is a disease of the central nervous system often diagnosed in early childhood. This is due to genetic mutation in one of the five genes. Changes in these genes may occur sporadically due to very high fever, head damage or infections. VWM can be hereditary and can run in families. Scientists
have identified genes that must be affected to cause disappearing white mass. In the group, these genes are known as the eukaryotic initiation factor 2b (EIF2B). The most commonly affected gene is the EIF2B5 gene. When there is a change in this gene, proteins can no longer do properly. Although mutation is the result of genetic factors, it can be accelerated or affected by specific events that affect the brain.
The progression of disappearing white matter is usually relatively slow, but certain events may worsen the condition and increase the speed at which mutations occur. The high fever, which is the result of infections, are the primary cause of dry Accelerations. TRAUMA HEADS PLACE CANstart a rapid deterioration of the patient's function. Even minor head injuries can be significant in a patient with this disorder.
The disappearance of white matter disorders causes the white matter of the brain, a collection of nerve fibers covered with oily insulator known as myelin. In individuals with VWM, cells in white matter are particularly sensitive to stress and hormonal changes in the body. As deterioration deteriorates, the symptoms of the disorder become more obvious.
If the change in the EIF2B gene is significant, motor and neurological function will be affected. This loss of function is a characteristic feature of disappearing white matter. The child can experience seizures, regular fever, stiff muscles and extreme fatigue. In addition, it can lose coordination, develop eye problems and have problems with cognitive functions and speech production. Finally, VWM will lead to a coma and death, usually resulting from a high fever.
the severity of the disease can be very different from čLuvka to man. Some children show symptoms of infant age, while others develop usually until later childhood. Movement problems are usually much more serious than getting to know and there may be long periods of constant development unless there is a decline. The average life expectancy ranges from a few years to the middle of the age of 40. Although there is no medicine for VWM, treatment focuses on alleviating many symptoms and preventing dangerous fever.