What is familial hemiplegic migraine?

Familiary hemiplegic migraine, also known as FHM, is a type of relatively rare migraine headache that causes weakness or compromised function on one side of the body or hemiplegia. The migraine is considered familial because it has a genetic component and thus runs in families; It should be noted that symptoms are often indistinguishable from a non -nave form of a disorder called sporadic hemiplegic migraine (SHM). Familial hemiplegic migraine is one of the more serious forms of migraine, with a wider range of symptoms and longer -term residual effects. Most classic migraines, however, do not include the signing hemiplegia of the familial hemiplegic migraine. Symptoms may also include ataxia or overall weakness of muscles; mental confusion; Visual interference; And sometimes the Suddkočánec EN that can imitate a stroke. In the classic migraine, symptoms usually stop at the end of the attack, but some symptoms of familial hemiplegic migraines can continue for hours or even days after the migraine itself. MigraThe éna may also occur without headaches. While most of the classic migraines begin around puberty or adolescence, family hemiplegic migraine may also occur in infants, usually presenting as convulsions. This type of migraine can also begin to distract during menopause, while classic migraines can often be lifelong.

The susceptibility to any kind of migraine is usually genetic, but the familial hemiplegic migraine is performed in the autosomal dominant gene , which means that you only need one parent with a dominant gene to transport a disorder. The diagnosis of familial hemiplegic migraine usually requires the patient to show most of the symptoms associated with with SHM and has at least one related first-grade-parent, child or sibling-infuting from symptoms. Genetic testing of familial hemiplegic migraine involves identifying mutations on ATP1A2, CACNA1A and SCN genes1a. Scientists have discovered three slightly different forms of migraine, known as FHM -1, -2 and -3. Each form maps the individual gene mutation.

Familiary hemiplegic and SHM migraine are more serious and potentially more dangerous than classical migraines, and therefore careful thinking and care should be devoted to their prevention and treatment. Most of the attacks on migraine are caused by a combination of external and internal triggers. Some triggers, such as emotional stress, can hardly avoid; Others, such as alcohol use, easily avoid. Migraine drugs usually fall into three categories: preventive medicines work to stop migraines before starting; Aborigative treatment attempts to stop migraines during the attack; And rescue medication is usually an analgesics and works to alleviate or camouflage pain until the attack has been attacked. Patients should discuss the possibilities with their doctors, especially because abortive drugs may lose their effectiveness over time.