What is a squamous intraepithelial lesion with a low degree?

Slopate intraepithelial lesions with low degree (LGSIL or LSIL) are abnormal growth in the surface layer of the cervix, especially in the transformation zone. They can be detected by Papanicolaa (PAP) test, which controls changes in cervical cells and increases changes in early detection of malignancy. Since the introduction of the paint in the mid -20th century, cases of cervical cancer have been decreasing, although it remains the main cause of death in women in developing countries. The examiner is looking for a squamous intraepithelial lesion with a low degree that is characterized by dysplasia. It is important to discover precancerous lesions because they can be treated to prevent progression to full cancer. The Bethesda system classifies precancerous cervical cells for squamous intraepithelial lesion with low degrees and a squamous intraepithelial lesion in high quality (HSIL). If it is not properly managed, up to 80% of squamous intra -epithelial lesions with a low degree can proceed to its high quality counterparts and 1% of them withE becomes invasive cancer. In cervical dysplasia, cell nucleus seem hyperchromatic or denser than usual and are clearly large due to cell size. Dysplastic cells look different from adjacent normal cells. They show pleiomorphism, which simply means they have variable shapes.

The occurrence of a squamous intraepithelial lesion with a low degree is associated with the infection of human papillomavirus (HPV). According to studies, the risk of LSIL and HSIL depends on the exposure to high -risk human papillomavirus. Subtypes that are considered to be low risk are HPV 6 and 11, while those that are considered a high risk are HPV 16 A18. Like other HPV variants, these viruses are transmitted by sexual contact. Have more sexual partners, be very young in the first sexual contact, be in the lower socio -economic layers and have a persistent infection with high -risk subtypes of HPVOna for the main risk factors of LSIL and HSIL.

To provide a definitive diagnosis of a squamous intraepithelial lesion with a low -degree, the uninterminated is visualized by a microscope using a method called colposcopy. A biopsy may be performed to exclude the possibility of malignancy. The aim of LSIL treatment is to kill abnormal cells on the cervical surface. Cryotherapy or application of very low temperatures on the uterine surface is often performed. When abnormal cells spread over a wide area, the entire area can be removed to reduce the risk of cancer.