What Is Acetylcysteine?
Acetylcysteine is a mucolytic agent with a strong mucolytic effect. The sulfhydryl group contained in the molecule can break the disulfide bond in the glycoprotein polypeptide chain in the sputum, thereby reducing the viscosity of the sputum and making the sputum fluid easy to cough. This product can also break the DNA fibers in purulent sputum, so it can dissolve not only white sticky sputum, but also purulent sputum. For patients whose general expectorant is not effective, this product can still be effective.
Basic Information
- Chinese name
- Acetylcysteine
- Foreign name
- Acetylcysteine
- Alias
- Xiaotanli, Fulu Shi, Yitan Yijing, etc.
- Specifications
- 0.1g (bottle), 5g (bottle)
- Indication
- Difficulty in expectoration
- Adverse reactions
- Cough, bronchospasm, nausea, vomiting, etc.
Acetylcysteine indication
- It is suitable for respiratory diseases characterized by excessive viscous secretions, such as COPD and bronchiectasis.
Clinical application of acetylcysteine
- Oral: 200 mg / time, 2 to 3 times / day; children 100 mg / time, 2 to 4 times / day.
Acetylcysteine adverse reactions
- Can cause cough, bronchospasm, nausea, vomiting, gastritis and other adverse reactions, reduce the amount can be relieved, in case of nausea, vomiting, can suspend medication. Bronchial spasm can be relieved with isoproterenol. This product can directly produce a large amount of sputum by dripping into the respiratory tract. If necessary, a sputum suctioner should be used to attract sputum.
Acetylcysteine considerations
- This product contains sugar, which is suitable for diabetic patients. The aqueous solution of this product is susceptible to oxidation and deterioration in the air, so it should be prepared immediately before use. Avoid taking powerful antitussive drugs at the same time. Granules of this product can be added with a small amount of warm water (hot water above 80 ° C is forbidden) or the juice is dissolved and mixed, or it can be taken directly orally. Should not be in contact with metal, rubber, oxidant, oxygen, so the sprayer must be made of glass or plastic.
Contraindications to acetylcysteine
- 1. Due to the sweetener contained in this product, patients with benzoic acid uremia are contraindicated.
- 2. Those who are allergic to this product, those with bronchial asthma, those with severe airway obstruction, and elderly patients with severe respiratory insufficiency are prohibited.
Acetylcysteine Drug Interactions
- The goods and iodized oil, chymotrypsin, trypsin incompatibility.
- Can improve the efficacy of the drug when used in combination or alternation with isoproterenol, reduce adverse reactions.
- Can improve the efficacy of the drug product when present in combination with isoproterenol or alternately, reduce adverse reactions.
- Nitroglycerin combined to increase the occurrence of low blood pressure and headaches. Acidic drug can reduce the effect of this product. This product can significantly increase the excretion of gold preparations, attenuated penicillin, tetracycline, cephalosporins antibacterial activity, it is not practical with these drugs, if necessary, can be 4 hours apart are used interchangeably.
- Note: The above content is only for introduction, the drug use must be carried out by a regular hospital under the guidance of a doctor.