What is agammaglobulinemia?
Agammaglobulinemia is an unusual type of immune system disorder in which the body does not create enough immunoglobulin (IG), which is an important antibody in the fight against bacteria and viruses. A person with a very low level of IG is highly sensitive to infections. In almost all cases, agammaglobulinemia is the result of a genetic mutation that is inherited from one or both parents. The disorder is usually observed in infants and children under the age of four who experience chronic diarrhea, frequent skin infections and several pneumonia or bronchitis seizures. Patients diagnosed with the condition usually receive regular intravenous IG injections to maintain their immune systems strong. BTK mutation seriously affects the ability of the immune system to produce IG and sometimes completely stops production. The vast majority diagnose patients with agammaglobulinemia are men whose parents have recessive BTK genes. In rare cases, a person may obtain a condition after suffering a serious infection or experience an allergic reaction to IMUno -depressive drugs. Patients are particularly susceptible to influenza viruses, salmonel and airway infections such as pneumonia. It means that the child may have agammaglobulinemia, include persistent skin infections, chronic diarrhea and severe bronchitis. The child may also suffer from frequent ear and sinus infections.
parents should look for a pediatrician's leadership if their child is experiencing frequent diseases and infections. The pediatrician may diagnose agammaglobulinemia by examining the child's medical history and taking blood samples to check the low level of IG. The physician may indicate that parents will be examined on BTK abnormalities to confirm the diagnosis. Once agammaglobulinemia has been confirmed, the pediatrician can explain the treatment options.
Agammaglobulinemia treatment usually involves injection of intravenous IG, which could come from donor blood or synthetic antibodies. Since Ig's production is in the transitionIt does not normally improve time, it is often required to get injections at regular intervals throughout their lives to prevent chronic health problems. Doctors also treat primary infections with oral and topical antibiotics. If the child's respiratory tract has been seriously damaged before frequent infections, it may have to undergo surgery to repair the damaged tissue. In regular treatments and controls, most children can recover from their symptoms and successfully maintain their health.