What is a chronic rejection?

Chronic rejection is a model of slow deterioration in the transplanted organ caused by the development of the immune response to the tissue in the organ. It is a form of long -term rejection of transplantation and is a particularly great cause of concerns with lung transplantation. For the reasons why scientists do not fully understand, patients undergoing lung transplantation are much more likely to experience chronic rejection, and the average survival of the lung recipients tends to be shorter than other donors for this reason. Donor body. Careful comparison is done to minimize the risks of rejection, in order to identify any possible conflicts between the donor and the recipient, but sometimes the risks are missed or considered acceptable if the alternative to While is waiting for a suitable donor organ.

Acute refusal sets within 60 days. Chronic rejection occurs after 60 days and is often slow. Over time an immune responseCE on the donor organ cause the development of fibrous tissue and may disrupt the function of the organ. Patients with lung transplantation may develop difficulty breathing and the patient's respiratory tract can narrow and clog with mucus. Symptoms of chronic rejection are usually identified during subsequent medical appointment and medical testing, such as imaging studies and biopsy, may be required to confirm the diagnosis of rejection.

In addition to the use of strict comparison systems for donor organs, doctors also provide patients with drugs intended to prevent rejection. These drugs suppress the immune function, making the body difficult to attack the donor organ. Chronic rejection sometimes found people take medication or cease to take them, although in other cases this occurs despite careful observance of the patient to therapeutic regime.

Potential complications of organ transplantation can send months or years after the transplantation procedure. It is important for patients to receive transplantRegular medical evaluation and carefully monitored instructions from their doctors. If patients notice signs of refusal, they should see a doctor immediately for thorough examination and evaluation. Catching rejection soon provides patients with more treatment options, including the opportunity to hit before a single treatment is a new organ to replace failing transplantation.