What is a family Mediterranean fever?

Familial Mediterranean fever is a hereditary disorder that affects people from the Mediterranean regions. This disorder tends to influence rivers, Armenians, Sephardi Jews, Turks and people of Arab origin. It is assumed that familial attacks on the fever of Mediterranean fever are caused by mutations of the MEFV gene.

MEFV gene is responsible for creating pyrin protein, which is a basic protein. Pyrin helps regulate inflammation in the body. If this protein is not a shortage, the body cannot effectively fight inflammation. Those who suffer from the Mediterranean fever lack pyrin protein. In some cases, fever attacks lead to hospitalization. The disease itself includes pain in the abdomen, chest and joint. Some patients occasionally reported scortal pain, myalgia, erysipeloid and fever without any other contributions. Most people who have familial Mediterranean fever will also experience symptoms of fever and rashes in times of severe pain. In general, attacks last anywhere from 12 to 72 hours and intensityThe attack will fluctuate depending on the person.

Treatment is essential to prevent further attacks. Those who do not seek the treatment of familial Mediterranean fever often experience a large amount of accumulation of protein, which can lead to kidney failure. Treatment of this disorder involves non -steroidal anti -inflammatory drugs such as colchicine therapy, often intravenous drop.

Familial Mediterranean fever is also known as periodic diseases, recurring polyseryitis, FMF and periodic peritonitis. This disease is relatively rare, although it is a serious condition that should be immediately solved. The Mediterranean fever is often incorrectly diagnosed because the symptoms of this disease may mimic appeticitis.

The diagnosis of the Mediterranean fever is often closed on the basis of a family history, an increased number of white blood cells and repeating symptoms. In addition, some patients may be given genetican test. While the Mediterranean fever is probably associated with the mutation of the MEFV gene, the reasons why this mutation leads to attacks on the Mediterranean fever is largely unknown.

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