What is gestational trophoblastic diseases?

Gestational trophoblastic disease (GTD) is a term for uterus tumors that develop from trophoblast - a layer of cells that surround the embryo during pregnancy. These cells normally develop in the placenta that adds nutrients to the fetus; In rare cases, however, they can instead develop into tumors. There are four primary types of gestational trophoblastic disease: Hydatidiform MOL, invasive mole, choriocarcinoma and placental place of trophoblastic tumor. This can also be caused by two sperm insecting eggs that contain DNA. The first type of fertilization does not create any fetal tissue at all and the second type can produce the fetus, but not a viable fetus. This type of gestational trophoblasty disease may occur in women who have been removed by hydatidiform moths. She is more common in women over 40 years of age. This type of GTD often spreads behind the uterus. It may develop from the HydatidIVIFIV pier, or may occur throughout the period of pregnancy or pregnancy that has been terminated early.

trophoblastic tumor on the place of the placental site is the most precious type of GTD. It occurs when the placenta connects to the uterus and usually occurs after pregnancy. These types of tumors usually do not expand behind the uterus and usually do not respond to chemotherapy.

sometimes exist when gestational trophoblastic diseases occur during otherwise viable pregnancy. In these cases, it is relatively rare to survive the embryo or fetus. Such pregnancies usually end in abortion or death of the fetus.

Gestational trophoblastic dishesis symptoms include abnormally large uterus, excessive vomiting, vaginal bleeding and preeclampsia. The disease usually occurs during routine ultrasound of pregnancy. It can also be diagnosed with a high level of human chorionic gonadotropin (HCG) in the blood. The diagnosis is usually confirmed by biopsy.

GTD is usually treated with surgery,chemotherapy or radiation. Tumors can often be sucked out of the uterus. Most women with GTD are able to have subsequent successful pregnancies.

Risk factors for GTD include getting pregnant before age 20 years or after the age of 40 years, abortion history and a history of difficulty of getting pregnant. Family history does not seem to play an important role, although many women with GTD have been reported in the family. Also, gestational trophoblastic diseases are slightly more common in women with blood type or AB than in women with blood type B or O.