What is hyperadrenocorticism?

hyperadrenocorticism is a disorder in which too much adrenocorticotropic hormone (ACTH) is present in the body, leading to a number of physical symptoms. In most cases, the surplus ACTH is the result of a benign tumor or other abnormality in the pituitary. The condition is most commonly observed in adults around 40 years, but the tumor may potentially develop and cause symptoms at any age. Patients diagnosed with hyperadrenocorticism usually have to undergo surgery to remove tumors and repair damaged internal structures. Cortisol is essential when checking physical reactions to stress, anxiety and illness. The surplus ACTH leads to cortisol overproduction, a state known as Cushing's disease. When the pituitary tumor develops, it can produce an extremely large amount of ACTH. Less commonly tumor in the lungs or elsewhere in the body can begin to produce independent Acthhypophysis. Torso, neck and face often become noticeably larger and round, while the legs remain relatively small. Pain and slaBost muscles are common in hyperadrenocorticism, as well as skin changes, acne and easy bruises. Women often have irregular menstrual cycles and men become infertile or impotent.

without treatment, hyperadrenocorticism can lead to high blood pressure, kidney stone formation and bone thinning. Bones can be sufficiently weak on a fracture with minimal pressure. In addition, changes in the mood, behavior and knowledge are common when the condition is left for several months or years.

The physician can usually diagnose hyperadrenocorticism by evaluating physical symptoms and take blood for control of ACTH surplus. Magnetic resonance imaging or computer tomographic scanning may be displayed to identify the tumor in the pituitary. The doctor may choose to extract a small tissue tissue sample to make sure it is not cancer. Treatment decision is usually made nand the severity of symptoms.

In most cases, symptoms of hyperadrenocorticism can be alleviated by surgical cut of matter in the pituitary. The ride can recover, but it may take years to return to its normal level of operation. The patient may need to take supplements or receive regular injections of the replacement of hormones during the recovery phase to determine normal ACTH and cortisol levels.