What is hyperammemia?

hyperammemia is a metabolic disorder that is caused by an excess of ammonia in the blood. Ammonia is a substance composed of nitrogen and hydrogen and is a major part of urea cycle, a process that concerns the transformation of ammonia into a less toxic organic compound called urea. Thus, an ammonia excess represents an increased level of toxic effects in the body. This is particularly affected by the central nervous system, which forms the main component of the nervous system, including the brain and spinal cord. Both are caused by a group of genetic diseases characterized by metabolic dysfunction caused by reduced enzymatic activity and subsequent increase in toxicity. In summary, the innate errors of metabolism, phrases created by British physician Archibald Garrod from the 19th and 20th centuries.

With primary hyperammemia, however, these ermyor occur in the urea cycle. An example of associated disorders is citrullinemia, which includes the accumulation of ammonia in the blood due to a lack of synthetase of argininosuccinic acid.Other examples include the lack of N-acetylglutamate synthetase, lack of ornithine translocases and arginase deficiency, each of which is named after the enzyme missing in the urea cycle. Secondary hyperammemia errors occur between the urea cycle. Two examples are methylmalone akysemia and propionic academic communities, which belong to the class of amino acid metabolic disorders known as the organic academy.

There are very few specific physical symptoms of hyperammemia. However, some medical scientists have noticed that infant patients usually show dehydration, lethargy, rapid breathing and reduced muscle strength. They also tend to develop larger than the usual fontanels, which are soft spots on the Thlebky issue, where the bone has not yet been created.

Doctors treat people with hyperammemia increasing ammonia excretion and at the same time reduce its income through pharmacological prescriptionOutbounds such as phenylace and sodium benzoate. Unexpected hyperamonemia can lead to encephalopathy, a brain disorder.

The most common form of encephalopathy induced by hyperammemia is liver encephalopathy. This condition, also known as portosystemic encephalopathy, is characterized by liver failure due to the fact that the organ is unable to handle excess ammonia among other toxic elements. Liver encephalopathy can lead to a coma and eventually to death. For such a condition it is always recommended to transplant liver or liver cells.