What is hyperkalaemic periodic paralysis?
hyperkalaemic periodic paralysis is a inherited genetic disorder that affects both people and horses. This disease is characterized by muscle weakness and temporary paralysis. Doctors and veterinarians treat the condition through diet and medicines. Sodium channels are specialized proteins that allow sodium ions to pass through cellular plasma membranes. Sodium and potassium cooperate in the body and create electrical signals that allow the muscles to download.
When the potassium levels increase and drop, the cells begin to leak sodium and potassium into the bloodstream. This causes the muscles to involuntarily download and create convulsions. Finally, the muscles lose their ability to withdraw and the patient suffers from temporary paralysis.
In horses, this condition is often called impressive syndrome in honor of a horse called impressive. Impressive was the champion in the classes of the halves was well known for its remarkable muscle structure. Its owners often managed to do horses who tried to improveof their supplies.
had a hyperkalaemic periodic paralysis and handed over the disorder to its many descendants. The condition is troubled by many quarters of horses, as well as Palominos, Appaloosas and other breeds that have been developed with a quarter magazine. Impressive disease will not miss generation and generally cannot be discarded or diluted.
hyperkalaemic periodic paralysis is autosomal dominant, which means that the patient must inherit only one copy of the gene to develop the disease. It affects both male and female horses at the same pace. Human men are more likely to develop a condition than women.
There was no drug for hyperkalaemic periodic paralysis found in early 2011. Horse owners prevent potential attacks by avoiding the feeding of high levels of potassium. Veterinarians treat the condition by prescribing drugs such as acetazolamide, a drug that regulates glucose and potassiumu in the blood.
The human patient is threatened by the development of hyperkalaemic periodic paralysis if he has parents or grandparents with this disease. The doctor may diagnose the condition by testing the amount of potassium in the patient's body. The doctor may also perform muscle biopsy or perform other tests to seek other conditions that could cause symptoms.
Doctors treat the condition by checking its symptoms. They prescribe acetazolamide, the same drug as horses to prevent episodes. They can also provide glucose to the patient to reduce the intensity of the attack.