What is malignant hyperpyrexia?

Malignant hyperpyrexia is a potentially life -threatening condition that develops in people exposed to general anesthesia drugs. Less commonly someone can develop a condition due to stress during exercise or exposure to extreme heat. The condition is also known as malignant hyperthermia or malignant hyperthermia syndrome.

Anesthetic drugs are amazed by the circulatory system of individuals who have malignant hyperpyrexia. Stress on the circulatory system can lead to death unless it is treated immediately. Symptoms of malignant hyperpyrexia include fast heart and respiratory frequency, increased carbon dioxide production and oxygen consumption, muscle rigidity, high temperature, exceeding 105 degrees Fahrenheit (40.5 ° C), increasing blood acidity and rapid collapse of muscle tissue.

Symptoms of malignant hyperpyrexia develop rapidly after exposure to anesthesia, usually within one hour, although in rare cases it may take several hours of symptoms for development. Dantrolen sodium treatment can reverse symptoms. DanumSodium roll is also administered to individuals with a risk of developing malignant hyperpyrexia, but must undergo general anesthesia for surgery; This usually prevents the onset of symptoms. Further treatment includes a cooling blanket to reduce temperature and introduce intravenous and oral fluids to prevent the kidneys from damage. Repeated incidences, even if it is quickly treated, can lead to kidney failure.

Malignant hyperpyrexia is a genetic state and having a family member with a condition increases the likelihood that others have a condition. Only one parent must carry a gene for malignant hyperpyrexia to give the property. Avoiding general anesthesia is the only way to prevent problems in the future.

Any cases of inexplicable death in anesthesia in the family should be an underneath of general anesthesia was hit by a health care provider. In addition, anyone who has a family history of muscle dystRofie or myopathy should consider genetic counseling before receiving general anesthesia. It is estimated that this condition may have 1 out of 100,000 individuals. The mortality rate is about six percent.

It is important to realize that general anesthesia drugs, namely a combination of anesthetic substances and neuromuscular blocking drugs, create a problem. Local anesthetics such as lidocaine and opiates, like morphine, will not start this condition. However, individuals who may have a genetic property for malignant hyperpyrexia should avoid cocaine, ecstasy, amphetamines and other stimulants that can cause similar symptoms.