What Is Meningoencephalitis?
Meningoencephalitis is because viral meningitis is an infectious disease of the central nervous system caused by a variety of different viruses, also known as aseptic meningitis or serous meningitis. Meningoencephalitis mostly occurs within the tenth disease day (65% -70%) after parotid enlargement. Approximately 25% of cases occur concurrently with parotid swelling and are seen worldwide. Its incidence is 11-27 / 100,000 per year. The clinical manifestations are similar. Meningeal irritation occurs mainly when it invades the meninges. Leukocytes, mainly lymphocytes, are found in the cerebrospinal fluid. The course of the disease was benign, mostly within 2 weeks, usually no more than 3 weeks, self-limiting, good prognosis, and no complications. Meningoencephalitis is formed when the virus invades the meninges and also the brain parenchyma.
Meningoencephalitis
Right!- Chinese name
- Meningoencephalitis
- Features
- Lymphocytic leukopenia
- nickname
- Aseptic meningitis or serous meningitis
- Incidence
- 11-27 / 100,000 per year
- Meningoencephalitis is because viral meningitis is an infectious disease of the central nervous system caused by a variety of different viruses, also known as aseptic meningitis or serous meningitis. Meningoencephalitis mostly occurs within the tenth disease day (65% -70%) after parotid enlargement. Approximately 25% of cases occur concurrently with parotid swelling and are seen worldwide. Its incidence is 11-27 / 100,000 per year. The clinical manifestations are similar. Meningeal irritation occurs mainly when it invades the meninges. Leukocytes, mainly lymphocytes, are found in the cerebrospinal fluid. The course of the disease was benign, mostly within 2 weeks, usually no more than 3 weeks, self-limiting, good prognosis, and no complications. Meningoencephalitis is formed when the virus invades the meninges and also the brain parenchyma.
- Meningococcal meningitis and meningoencephalitis mostly occur in
- The main signs are swelling of the parotid and submandibular glands, redness and swelling of the parotid ducts, neck resistance, Krebs sign, and Pasteur's sign are positive. A few patients may have nystagmus, ataxia, and lower limb weakness.
- The appearance of cerebrospinal fluid examination is clear, the pressure is normal or slightly higher, and the number of white blood cells increases, most of which are 300-500 / cubic millimeter, and occasionally more than 1000-2000, and the number of early neutral cells increases. After the second disease day, lymphocytes are predominant, sometimes reaching 80% to 100%. The protein content is slightly higher, and sugar and chloride are normal. If the above changes are not easy to make a pathogen diagnosis before the parotid gland enlarges, virus isolation from cerebrospinal fluid is the most reliable diagnostic basis. In recent years, the detection of cerebrospinal fluid-specific immunoglobulin M antibodies using enzyme-linked immunosorbent assays can help confirm the diagnosis.
- The damage to the central nervous system of the gills is directly caused by the gills virus in the early stage of onset. On the basis of viremia, the virus damages the central nervous system through the blood-brain barrier. The chance of damage is proportional to the extent and duration of viremia. Some meningoencephalitis occurs within one to two weeks or even one month after the disease, and its pathogenesis may be caused by a neurological reaction or an autoimmune reaction.
- In order to reduce morbidity and complications, patients should be isolated early and rested properly. Active treatment measures should be taken once neurological symptoms appear.