What is metachromatic leukodystrophy?

Metachromatic leukodystrophy, also known as billion, is degeneration or a change in the white matter of the central nervous system and brain. It is part of a family of genetic disorders called leukodystrophy that disrupts the way myelin cloak grows or evolves. In metachromatic leukodystrophy there is a lack of arylsulphase A. Arylsulphasis and decomposes sulfatide; However, when it does not break down, sulfatides are formed to toxic levels and poison the nervous system, brain, kidneys and liver - which deteriorates them. If metachromatic leukodystrophy is when a person is adult, it generally occurs after sixteen years. The first symptoms for the initial form of billions are personality changes, behavior changes, reduced ability to think or perform daily functions, dullness of hands and feet, and meetings problems. It is often incorrectly diagnosed as a psychiatric state or form of dementia. It has the slowest procedure - where the decline can continue for decades - any forms of billions.

In a youthful form of metachromatic leukodystrophy, the patient is influenced between three and ten years. They usually start playing badly at school, show signs of dementia and suffer from mental deterioration. Like the adult beginning of BLD, patients also have problems with their walking, changes in behavior and reducing intellectual capacity. In addition, they may suffer from seizures or muscle convulsions. Although this proceeds slower than a late infantile form, death may occur between ten and 20 years after symptoms first occur.

The most common form is also the most common form of metachromatic leukodystrophy, late infantile billion. Children are usually affected by him for one year; In many cases, however, symptoms may not occur until they are four years old. Symptoms include muscle worsening, too rigid muscles, developmental delay, decrease in vision until the patient is monitored, convulsions, paralysis, swallowing and dementia. Unfortunately, children can fall into a coma and mostIna of them does not live five to ten years when the symptoms begin.

There is currently no treatment of metachromatic leukodystrophy. In some cases, the patient may receive bone marrow transplantation to slow down the disease progression; However, it must be caught in time to become a useful action plan. Other steps can be taken to give the patient better quality of life and treat symptoms. These steps include drugs to reduce symptoms and relieve pain, surgery to relieve pain in the areas of body influence, physical therapy, ergotherapy, speech therapy, recreational therapy, auxiliary equipment, eye inspections and gallstones. Research is conducted to learn more about the disease and how to treat it.