What Is Paget's Disease of the Breast?

Paget's disease is a malignant tumor of the nipple and surrounding skin in middle-aged and elderly women, also known as extra-mammary eczema-like cancer. Early treatment has a good prognosis. Occasionally seen in men.

Paget's disease

Paget's disease is a malignant tumor of the nipple and surrounding skin in middle-aged and elderly women, also known as extra-mammary eczema-like cancer. Early treatment has a good prognosis. Occasionally seen in men.
Western Medicine Name
Paget's disease
Other name
Extramammary eczema-like carcinoma
Disease site
Vulva, scrotum, perianal, armpit
Multiple groups
Occurs in middle-aged and elderly women, occasionally in men
Paget's disease
Paget's disease
Often unilateral. The erythema appears as an infiltrating Perry-class frigate, with scales, crusts, and exudation. The skin lesions are clear and gradually spread to the surrounding skin. Lesions develop slowly, and early changes are similar to eczema and can be misdiagnosed as eczema. It is now clear that most of the eczema-like cancers of the breast are caused by the ductal cancer of the breast going up to the epidermis. Therefore, all patients with eczema-like cancers should be palpated carefully to check whether there is a lump in the breast. It is advisable to treat with a simple mastectomy, and if necessary, the attached axillary lymph nodes should also be removed.
Extra-mammary Paget's disease is also called extra-mammary eczema-like cancer. Both sexes can be encountered. It is found in the vulva, scrotum, perianum, axillary and other parts. The clinical manifestations are similar to breast Paget's disease, with eczema-like appearance. It is thought that extramammary Paget's disease may originate from sweat gland epithelial cells, and part of it is directly extended from rectal cancer and cervical cancer. Treatment can be surgically resected. Larger patients need skin grafting after resection, and the radiotherapy effect is also good.

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