What is rapidly progressive glomerulonephritis?
rapidly progressive glomerulonephritis (RPGN) is a condition that adversely affects kidney function and can quickly become life -threatening life. RPGN, also known as a crescent glomerulonephritis, is often associated with existing kidney disease and inflammatory conditions such as vasculitis. The treatment is entirely dependent on the basic cause of inflammation. In most cases, drugs can handle symptoms and slow renal failure progression. Acute cases may require dialysis and kidney transplantation.
The diagnosis of rapidly progressive glomerulonephritis is generally performed by laboratory testing. Blood panels and urine analysis are usually given to assess the function of kidney and control inflammation and infection. The signs of glomerulonephritis often include a crescent -shaped glomeruli, elevated creatinine levels and the presence of antibodies associated with RPGN. In addition, protein will be inadequate in the blood, but excessively high in the urine. A kidney needle biopsy may also be performed to determine prevalencescarring or other physiological abnormalities. It is the responsibility of these capillaries to filter blood dirt. After separation, toxins are processed and eliminated as urine. In the presence of glomerulonephritis, the capillaries are ignited, allowing dirt to slip and stay in the blood. The accumulation of contaminants exhausts the blood circulation of the basic nutrients.
individuals with existing kidney and inflammatory diseases are the greatest risk of developing rapid progressive glomerulonephritis. In some cases, severe or chronic bacterial infections may also damage glomeruli, contributing to the inflammation and onset of RPGN symptoms. Chronic Condipozvy, which causes scarring of tissue, such as kidney -based diseases, often threatening kidney function, leading to the development of RPGN. It is not uncommon for some cases to be diagnosed as idiopathic, which means that there is no definite for its onsetThe reason.
symptoms of acute impaired kidney function often represent a significant retention of fluids and swelling on the lower limbs, namely ankles and feet. Individuals with rapidly progressive glomerulonephritis noticed that urine less often, but when they do it, urine can be loaded with protein. It is not unusual that some people secrete blood or dark, unusually colored urine. The impaired glomerulululi function often allows red blood cells to pass into the urine, which is known as hematuria, which makes urine dark. As a person's condition deteriorates, anemia can develop, causing it to easily get tired or feel weak with little physical activity.
Fast progressive glomerulonephritis treatment is focused on alleviating the basic cause of inflammation and slowing the disease progression. Immunosuppressive and steroid drugs are generally administered to reduce inflammation and relieve symptoms. If the glomerululi damage comes from an infection, antibiotics may be administered. DIlying and plasmapheresis can be used to systematically remove toxins and antibodies based on RPGN from the system, which further reduces inflammation and releases the kidney tension. Individuals with a rapidly progressive end stage related to glomerulonephritis or complete kidney failure can undergo transplantation.