What is the connection between cystic fibrosis and diabetes?

Cystic fibrosis is a inherited condition that affects many body systems. The disease causes problems with the function of the pancreas that can lead to diabetes over time. The diagnosis and treatment of diabetes observed in patients with cystic fibrosis is similar to diabetes rooted in other causes. The basis of the treatment of diabetes related to cystic fibrosis is subcutaneous insulin.

Cystic fibrosis is a genetic disease caused by mutation in gene coding for chloride channel. In normal people, the chloride channel is widely distributed throughout the body, but there are no copies of this chloride channel in patients affected by cystic fibrosis. As a result, they develop a number of medical complications affecting respiratory tract, nasal cavity, skeleton, reproductive tract, biliary system and pancreatic pancreatic. Due to the lack of normal chloride channels, the patient's pancreas Cystic fibrosis cannot produce the right digestive enzymes. The poor functioning of the pancreas over time leads toRecurrent seizures of pancreatitis and to reduce the production of pancreatic enzymes and hormones. This eventually leads to the loss of the endocrine function of the pancreas, which includes its role as an insulin secretor.

patient with cystic fibrosis, whose pancreatic pancreatic does not have the ability to produce insulin, is considered to be diabetes related to cystic fibrosis (CFRD). Approximately 25 percent of patients with cystic fibrosis have cystic fibrosis and diabetes at the age of 20 years and the incidence of CFRD increases with age. Patients with this disease live with progress in other aspects of cystic fibrosis treatment. As a result, the number of people with cystic fibrosis and diabetes is growing.

symptoms of diabetes related to cystic fibrosis may incarnate high blood glucose, increased thirst, increased urination, loss of peripheral feeling and reduced vision. The condition can be diagnosed with inspection of blood glucose levels on an empty stomach, performedImage oral test tolerance of glucose or control of glycated hemoglobin levels. Some doctors who take care of patients with cystic fibrosis of adults are regularly reflected in CFFD because of its high prevalence.

Cystic fibrosis -related diabetes is often treated with subcutaneous insulin. In some respects, the CFRD is similar to diabetes mellitus type 1, a pathological condition in which patients have autoimmune destruction of pancreatic cells that create insulin. As in patients with type 1 diabetes mellitus requires survival of exogenous insulin, patients with cystic fibrosis and diabetes also require insulin injections.