What is the connection between gluten and arthritis?
gluten is a protein that often occurs in grains such as wheat. These proteins can play a role in some types of arthritis. The connection between gluten and arthritis suggests that the body can mount an allergic response to the protein. This response could sometimes be the cause of inflammation and pain found in rheumatoid arthritis and other related conditions.
rheumatoid arthritis includes an incorrect immune response that focuses on joint tissue in the body. Some research combined arthritis with diseases such as inflammatory bowel disease and celiac disease. Both of these diseases often include gluten intolerance. Gastrointestinal problems resulting from gluten consumption can lead to the activation of the immune system, leading to subsequent attacks on joints and connective tissue.
Celiac diseases usually have one gluten -known problems known as gliadin. During celiac disease, the body creates antibodies that focus on gliadin. When an individual eats food with gluten, the presence of whoeverPlexes gliadin-signs cause immune cells to “turn on” and target nearby cells for destruction. This causes intestinal damage.
A similar mechanism involving gluten and arthritis has been examined in one study. Participants of this study had celiac disease and rheumatoid arthritis. Hours after a meal based on gluten -based wheat experienced greater degrees of pain and inflammation.
scientists found that gluten, as well as peptides created in digestion of these proteins, moved from the intestine to the bloodstream. The antibodies that specifically tied these proteins and peptides have created large molecular structures called immune complexes. These complexes signaled to nearby cells to mount the immune response in the body.
immune responses connecting gluten and arthritis begin with blood plates, specific type of blood cells. Plates release chemical serotonin that promotes the arrival of white blood cells,that cause inflammation. Immune complexes tend to collect in the joints, and therefore the resulting response affects the connective tissue in these areas. It is believed that serotonin increases the chances of immune complexes that reach the joints, thereby locating damage to these areas.
The connection between gluten and arthritis has led some health experts to propose dietary changes in an effort to alleviate symptoms. At least one study found that a gluten -free diet led to minor joint pain and inflammation in individuals with arthritis. Scientists believe that this reduction in symptoms may be due to the absence of an immune response regarding gluten and arthritis. They also state that this diet could lead to the body to create some anti -inflammatory antibodies that could reduce symptoms.