How effective is Azathioprin for ulcerative colitis?

Azathioprine administration for ulcerative colitis may be beneficial and effective treatment in some cases. Azathioprine is effective in the treatment of ulcerative colitis because the drug works by suppressing the excessive immune system that causes this disease. The main example in which effective administration of azathioprin for ulcerative colitis is to allow doctors to reduce the dose of drugs called corticosteroids that are commonly administered for the disease. Although corticosteroids may prevent symptoms, long -term use in high doses may have harmful side effects.

Azathioprin use for ulcerative colitis has been shown as a number of different patients suffering from this disease. It is effective because it changes the immune system of the body. Specifically, it inhibits the process of forming deoxyribonucleic acid (DNA) in the body and selectively inhibits the activity of some white blood cells that play roles in the body's immune system. Because ulcerative colitis is autoimmune oSickness, which is partly caused by an excessively active immune system that attacks the native parts of the human body, leads to the suppression of the body's immune response to clinical regression of the disease.

Not all patients with ulcerative colitis should be treated with azathioprin. This medicine has the most usefulness when it is given to help maintain the remission of the disease. Patients with ulcerative colitis tend to have eruption of disease activity and experience acute impairment of symptoms, including bloody diarrhea, abdominal pain and fever during these eruptions of the disease. The light itself is often treated with medicines called corticosteroids to calm the activity of the disease and allow remission. Corticosteroid doses decrease as tolerated when symptoms begin to disappear.

If patients cannot fully be fully out of the possibilities are corticosteroids after acute flare and use azathioprin for ulcerative colitiDu. Adding this drug often allows doctors to reduce corticosteroid doses, which is beneficial because long -term use of corticosteroids can have significant side effects. In some cases, the addition of azathioprine allows patients to completely remove corticosteroid treatment. However, some experts consider the use of Azathioprin itself and recommend continuing to use both corticosteroids and azathioprin to prevent other worlds of disease.

Once an objection to azathioprin for ulcerative colitis is that several different blood tests should be performed before starting this drug in patients suffering from this inflammatory intestinal disease. Either Thiopurin Methyltransferase (TPMT) or the genetic sequence that encodes TPMT must be evaluated before therapy starts. Patients dreamed activity Smpt should not be treated with azathioprin because it could experience more toxic effects in the administration of this drug.