What Are the Different Sources of Natural Melatonin?
Melatonin (also known as melatonin, melatonin, melatonin, and pinealpine) is an amine hormone produced by the pineal gland of mammals and humans. The cells glow and are named melatonin. It is found in a variety of organisms, from algae to humans, and its level varies with the time of day.
- Chinese name
- Chinese name: Melatonin
- Foreign name
- English: melatonin
- Alias
- Melatonin, melatonin, pinealpine
- CAS number
- 73-31-4
- Chemical Name
- N-acetyl-5-methoxytryptamine
- The molecular formula is
- C13N2H16O2
- Molecular weight
- 232.27
- Melting point
- 116 118
- Melatonin (also known as melatonin, melatonin, melatonin, and pinealpine) is an amine hormone produced by the pineal gland of mammals and humans. The cells glow and are named melatonin. It is found in a variety of organisms, from algae to humans, and its level varies with the time of day.
1 Melatonin 1, sources of melatonin:
- A hormone substance that can lighten the color of skin pigments. This hormone is synthesized in the pineal gland with tryptophan as its matrix, and its chemical names are N-acetyl and 5-methoxytryptamine.
- Melatonin is the first biologically active substance found in the pineal gland. When mammals are in the dark, melatonin secretion activity is immediately strengthened; when it is turned into a light environment, it stops secreting. The rhythm of melatonin secretion can be measured from urine with changes in light. Other factors such as sleep, diet, mental state, and stress also have an effect. Injecting melatonin into the hypothalamus can inhibit gonadotropin secretion, but it has also been observed that melatonin can directly affect the pituitary. Therefore, melatonin can inhibit gonadotropin secretion through the hypothalamus and / or pituitary. In addition, melatonin receptors have also been found in the ovary, indicating that this is also the site of melatonin action.
2 Melatonin 2, the main uses of melatonin:
Melatonin delays aging:
- Free radicals may be generated during enzymatic and non-enzymatic reactions in the body. Free radicals are closely related to aging. The production and elimination of free radicals in the normal body is in a dynamic balance. Once this balance is broken, free radicals can cause damage to biological macromolecules such as lipids, proteins, and nucleic acids, leading to the destruction of cellular structures and the aging of the body. Melatonin protects cell structure, prevents DNA damage, and reduces the level of peroxides in the body by eliminating free radicals, anti-oxidation and inhibiting lipid peroxidation. Studies by some scholars have found that melatonin can protect DNA damage caused by safrole (a carcinogen that damages DNA by releasing free radicals) up to 99% in a dose-response relationship. Melatonin has a significant antagonistic effect on tissue damage caused by peroxidation caused by exogenous toxicants such as paraquat and free radicals generated. Melatonin can also reduce the content of LPO in the brain. Its effects in different regions of the brain, such as the cerebral cortex, cerebellum, hippocampus, hypothalamus, and striatum, are basically the same, and they are dose-dependent. But different strains of rats such as Sprague-Dawlay and Wistar rats have different sensitivity to melatonin.
Melatonin improves sleep:
- It can shorten the awakening time before going to bed and the time to fall asleep, improve the quality of sleep, the number of awakenings during sleep is significantly reduced, the light sleep stage is short, the deep sleep stage is prolonged, and the threshold for awake the next morning is reduced. Has a strong function of adjusting jet lag. It is mainly used in whitening and moisturizing cosmetics, and is also commonly used in hair products. Extensive research has been carried out at home and abroad on the biological functions of melatonin, especially as a health supplement for dietary supplements. It has been shown that it has many physiological functions such as promoting sleep, regulating jet lag, anti-aging, regulating immunity, and anti-tumor. The health functions of melatonin at home and abroad involve regulating endocrine (inhibiting ovulation), protecting the encephalitis virus infection and reducing its post-infection mortality, AIDS treatment and cardiovascular protection.