What factors affect sufficient dosing of vancomycin?

Vankomycin, a strong antibiotic drug used to treat a number of different infections, can be difficult to administer correctly. Many factors affect the correct dosing of vancomycin, including the patient's weight and how well its kidneys work. Vankomycin levels in the patient's blood are often monitored because they are treated with this drug. Although vankomycin is usually administered as an intravenous drug, it can also be administered as an oral medicine.

The most important factor affecting vancomycin dosage is the body's body weight of the patient. In order to calculate how much this antibiotics it requires, it is important to know its current weight, either in pounds or kilograms. Patients are usually given 66-132 milligrams (mg) on ​​the pound (LB) or 30-60 mg per kilogram (kg) per day. This overall daily requirement is often distributed into several doses, for example two doses, each containing 33-44 mg per pound (15-20 mg per kg) per day.

and Person's dose of vankomycin is also affected by how well they workits kidneys. Medicines are removed from the body by the kidneys, and if these organs do not work well, it tends to build a high level in the body. This can be dangerous because vancomycin can cause body damage at high doses. Patients with impaired kidney function are therefore generally administered by reduced dosage of vancomycin, which is treated on the basis of their basic renal function.

Some people have differences in how their body metabolizes and gets rid of vankomycin. For this reason, it is common in hospitals to monitor the level of vankomycin in the patient's blood during treatment. The level of the riverbed vankomycin is often checked. The drug concentration is checked half an hour before administration of the morning dose of the third day of treatment. This value should fall within a certain range to be considered therapeutic vancomycin; If this is not the case, the subsequent doses may be increased or slower.

Although vankomycin is usually administered as an intravenous medicine, which means that it is served as a solution directly to the patient's veins, in selected infections it is given as a medicine used by the mouth. Gastrointestinal tract infection, such as colon infection known as colitis, responds better to vankomycin when served orally. Patients taking drugs by mouth take 500-2,000 mg of vancomycin a day, each with a part of this total daily dose every six hours.