What is a donor comparison?
Donor comparison is the process of choosing compatible donor blood, tissues or organs for transplantation to another person. It begins with the identification of tissues and blood types of the recipient and donor, and then by storing information in the database for the National Donor Comparison Program. The size of the organ, the blood type and the type of tissue must correspond to both donors and recipients so that the transplantation is successful. After meeting the initial criteria for writing, the transplant agency will take into account the amount of time spent on the waiting list, the urgency of the person's health and the distance that the person lives from the donated authority.
The first step compared to the donor is to write blood and the tissue of the potential donor and the recipient of the transplant. There are four main types of blood, A, AB, B and O. Compatible types of blood are carefully proven due to life -threatening complications that can occur when the wrong blood type is mixed.
Another in the donor comparison process is tissue writing. Human leukocyte antigens (HLA) are present in the bloodstream and are used to indicate tissue types. The aim is to compare six of these GLAs, such as HLA-A, HLA-B and HLA-DR. Given the development of medicines against rejection, a person may still be eligible to receive a donated organ, even if the antigens do not match. Donated authorities with a perfect match of all six voters have a longer survival of transplantation than the organs that are maintained by medicines against rejection.
Another test in the donor comparison process is the blood test for the reactive antibodies of the panel (pig). If a person has a high level of antibodies in his blood, the condition is also called highly sensitized; He is likely to have difficulty comparing a compatible donor. High levels of PA can be caused by previous blood transfusion or it can start after a woman was pregnant. A medical procedure called plasmaphesis that removes human blood and fIt illustrates antibodies from it, it can become some highly sensitized patients to become suitable candidates for transplantation.
Another screening test for donor comparison is called cross comparison. During this test, blood from the donor is mixed with white blood cells of the potential recipient. If the test is positive for comparison of the cross, white blood cells will be attacked and destroyed by the donor's blood antigens. The negative result of the cross comparison means that the donor and recipient are compatible matches.