What is the most common procedure for bone marrow transplantation?
The most common procedure of bone marrow transplant is autologous bone marrow transplantation. With this type of transplant, the patient serves as his own bone marrow donor. Autologous transplantation can also be performed using stem cells of peripheral blood of the patient. This option is known as autologous stem cell transplantation in peripheral blood or autologous stem cell transplantation. Bone marrow transplantation and stem cell transplantation are often used interchangeably. Because bone marrow lies in the center of bones, the patient is soothed through general or regional anesthesia. During the surgery, the doctor puts the needles into the pelvic bone or thoracic bone to extract the pulp. The harvested pulp is then processed to remove any blood or fragments of the bone.
Unlike autologous bone marrow Sprant, autologous stem cell transplantation does not include surgery. TOMency cells are harvested from the bloodstream by a process called Afesis, also known as leukaphesis. For preparation for afferes, the patient is given four to five days of a drug called a factor stimulating granulocytes (G-CSF), which stimulates bone marrow to release more stem cells into the bloodstream. The patient's blood is then removed with a large vein in the arm or a central veneer catheter, a tube that is inserted into a vein in the neck, chest or groin. The patient's blood is further processed through a machine that filters out stem cells and returns blood to the patient.
both harvested bone marrow stem cells and peripheral blood can be preserved and freezing using a technique called cryoconzervation. The patient then undergoes a preparatory or conditional region, which consists of chemotherapy and less frequently radiation. The purpose of preparations for transplantation is to completely eliminate patient cells from the patient's body. Other cells are also eliminated during this process, hopefully they allow transplanted bone marrow notBo stem cells to create an improved immune system that provides effective treatment against the patient's disease.
during the actual procedure of autologous bone marrow transplantation, as well as in autologous stem cell transplantation, harvested and processed cells are transplanted back to the patient by the central venous catheter. The cells then pass through the bloodstream and create a new bone marrow into the spaces inside the bones. Because there is no risk that the body will reject its own cells, autologous transplantation is considered safer and has become more common than allogenic bone marrow transplantation, where bone marrow or stem cells from the donor are used. Autologous bone marrow transplantation or stem cells can be prescribed to treat any of the different Diseases, including Ewing's sarcoma, lymphoma and some brain tumors.