What Is Troglitazone?

Troglitazone is a ketone drug used to treat type 2 diabetes.

Troglitazone

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Troglitazone is a ketone drug used to treat type 2 diabetes.

Drug Name

Troglitazone

Alias

Rizelin

Foreign name

Noscal, Rezulin

Whether prescription drugs

prescription

Main indications

Troglitazone side effects; aliases: rezelin, Noscal, Rezulin; troglitazone indications: used to treat type 2 diabetes. ; Troglitazone pharmacological effects: This product is thiazolidinediones, which can improve

Primary classification: endocrine system drugs

Secondary classification:

Troglitazone

Rezelin, Noscal, Rezulin

Tablet: containing troglitazone 0.2g

This product is thiazolidinediones, which can improve

Oral absorption is good, absorption is good when ingested with food, the peak time of plasma drug concentration is 3h, and plasma half-life is 16-34h. This product is metabolized in the liver, and the metabolites are partially active. Mainly excreted by feces. Plasma drug concentrations in patients with liver dysfunction can increase several times.

For the treatment of type 2 diabetes.

1. Banned for pregnant or lactating women.

2. Alcoholics,

Liver function should be regularly checked before using this product or every 2 months during use. If the ALT value is 2 to 3 times longer than before taking the drug, the drug should be stopped immediately.

Adverse reactions showed a slight reversible increase in ALT, which occurred in 2 of 2510 cases abroad.

Oral, the initial dose of 0.2g each time, once a day, taken at the main meal or between meals. After 4 to 12 weeks of treatment, the effect is not satisfactory. The dose increase is 0.4 g each time, once a day, and the maximum dose is 0.6 g per day. Blood volume will increase by about 6% to 8%, and triacylglycerol will tend to decrease when insulin is added to this product. versus

Combining with cholestyramine will significantly reduce the absorption rate of this product, reducing the absorption rate by 70%. Combined with terfenadine, it can lower the plasma drug concentration of the latter.