What Are Peptide Bonds?

Peptide bond is an amide bond formed by the dehydration condensation of the -carboxyl of an amino acid and the -amino of an amino acid, that is, the bond represented by the second "-" in -CO-NH-. Amino acids are linked into peptide chains by peptide bonds. It is the main covalent bond in protein molecules and is relatively stable in nature. Although it is a single bond, it has the property of a partial double bond. It is difficult to rotate freely and has a certain degree of rigidity. Therefore, a peptide bond plane is formed, including 6 CO, N-H, and 2 C connecting the two ends of the peptide bond. The space position of the atom is on a relatively close plane, and the side chain R of two adjacent amino acids forms a trans configuration, thereby forming a complex spatial structure of the peptide bond and the peptide chain.

Amide bond is a negatively charged functional group. In organic chemistry, the amide bond is -CO-NH-, where carbon and oxygen form a double bond and nitrogen and hydrogen form a single bond. Peptide bonds are all amide bonds. Amide bonds include but are not equivalent to peptide bonds. The amide bond refers to a larger range than the peptide bond.

Peptide bond is an amide bond formed by dehydration condensation of -carboxyl group of one amino acid and -amino group of one amino acid, namely -CO-NH-. Amino acids are linked into peptide chains by peptide bonds. It is the main covalent bond in protein molecules and is relatively stable in nature.

Although it is a single bond, it has the property of a partial double bond. It is difficult to rotate freely and has a certain degree of rigidity. Therefore, a peptide bond plane is formed, including 6 CO, N-H, and 2 C connecting the two ends of the peptide bond. The spatial position of the atom is on a relatively close plane, and the side chain R of two adjacent amino acids forms a trans configuration, thereby forming a complex spatial structure of peptide bonds and peptide chains ^[2] .