What is beta amyloid?

beta amyloid protein is a large peptide containing 39 to 43 amino acids. This peptide chain is assumed to play a major role in the development of Alzheimer's disease. The plaques that develop in the brains of people with Alzheimer's disease are mainly composed of beta amyloid peptide. This peptide can also play a role in the development of other neurological diseases such as Lewy Body Dementia. The more common form of peptide has only 40 amino acids, but Peptide 42AA tends to create plaques. The plaques are formed because the protein is fibrilogenic, which means that it tends to cluster together with other proteins to form fibrous structures. These structures are plaques that gradually inhibit normal brain function in humans with Alzheimer's disease. Samy is in the neurons in the brain. Once the fibers are connected, neurons prevent signals from other cells in the brain. The affected neurons cannot work or communicate with other brain cells and, as a result, die.

Alzheimer's disease is partially genetically inherited, a feature associated with the tendency to produce beta amyloid peptides with a length of 42 amino acids. When an individual has one copy of a gene that produces peptide 42AA, it has an increased risk of developing Alzheimer's disease. The person with two copies of this gene is exposed to the high risk of developing the early onset of Alzeimer.

Based on this knowledge of how the protein interacts to create plaques, scientists came up with several ideas that are examined as potential therapies to treat Alzheimer's disease. One of them is an enzyme called beta-secretaze inhibitor. This enzyme can be able to block the cleavage of amyloid protein into the 42AA form, which is strongly associated with the development of Alzheimer's disease. The related idea is the enzyme of gamma-secretazy, which prevents the formation of peptide 42AA at another point of the production cycle.

Another approach to the treatment of Alzheimer's diseaseIt is the development of beta amyloid antibodies that can recognize and bind to Peptide 42AA. These antibodies can be able to bind to a peptide and prevent it from creating plaques. In addition, the antibody can help promote peptide destruction, as the immune system will destroy the antibodies of the antibodies that are formed.