What Is a Point Mutation?
A point mutation is when only one base pair changes. Generalized point mutations can be base substitutions, single base insertions, or base deletions; narrow point mutations are also called single base substitutions. Base substitutions are divided into transitions and transitions. Point mutations have a high rate of back mutations.
Point mutation
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- Chinese name
- Point mutation
- Foreign name
- Point mutation
- Also known as
- single
- A point mutation is when only one base pair changes. Generalized point mutations can be base substitutions, single base insertions, or base deletions; narrow point mutations are also called single base substitutions. Base substitutions are divided into transitions and transitions. Point mutations have a high rate of back mutations.
- Can be divided into transitions and
- Conversion:
- Sickle-cell disease is typically a disease caused by point mutations.
- The point mutation of wheat waxy gene resulted in a significant decrease in amylose content in the grain.
- The increase or decrease of one or a few pairs of contiguous nucleotides in the base sequence of DNA caused a series of coding changes after this position to become frameshift mutations, as shown in the following table:
T | A | C | C | C | A | T | T | A | |
T | A | C | (Missing a C) C | A | T | T | A |
1. During DNA replication
- Sickle-cell disease is typically a disease caused by point mutations.