What are the causes of the progeries?

The causes of progeries are abnormalities in the nucleotide structure of the DNA of the affected children. These abnormalities are the result of mutation in the LMNA gene, which is responsible for the production of proteins that surround the cells of the cell. It is believed that the final structural instability of the core causes aging symptoms that experience people with this syndrome.

The progeria is a genetic disorder that causes premature aging in young children. Children are born with this disease that seems to be healthy and begins to slow their normal growth rate at the age of 18 to 24 months. Their bodies gradually experience hair loss and body fat. Skin begins to take an old man, as the syndrome progresses, and their joints become stiff, and sometimes lead to hip dislocation. Most children born with this genetic abnormality die of heart disease and stroke around 13 years, although several cases survived until the age of 20.

Vgen lmna mutation is considered one of the primary causes of the progie. Lmna gene produces protein lAmin A. This protein is one of the structural spine that surrounds and provides support of the cell core. Doctors and scientists believe that the resulting instability of the core leads to symptoms of premature aging.

Genetic mutation initially manifests itself in one small change in DNA nucleotides. Nucleotides are building blocks of chain structure that is DNA and consists of adenin, guanine, thymine and cytosine. Changing in nucleotide sequence, which is one of the causes of the progie, is to replace thymine for cytosine in the 1824 position.

Although the dominant genetic property for priegery is not inherited. Children who develop this mutation are not born to parents who have abnormality. Resnacles believe that a mutated code that changes a nucleotide sequence can occur in an egg or in one sperm immediately before conception.

Research of the causes of the proger is underway. Genetic abnormalIta, which is assumed to cause a rapid aging process, was identified in 2003 as a common link shared by mostly suffering from illness. Scientists are not entirely sure how laminate and protein concern the overall aging of a person. There is no medicine to slow down adequately and reverse the side effects of aging in diagnosed children.

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