What is the refusal of Stepa?
The refusal of graft is the immune response of the body to destroy foreign cells in the transplanted tissue. The graft rejection occurs because the transplanted tissue or organ has antigens on its cells that do not match the person's own cellular antigens. Only grafts from one identical twin to another are perfect matches, so most patients with grafts must take immunosuppressive drugs to prevent their body from rejecting the graft. The graft can be from anywhere on the patient's body, for example in the case of skin grafts. The graft can come from a corpse, for example in the heart or transplant of the liver or from a living person, as is the case with many kidney and bone marrow transplantation.
As mentioned, the best grafts in terms of corneal transplant rejection is unusual because they are rarely rejected. This is because the cornea does not have a blood supply, and therefore the corneal molecules do not reach the cornea. The patient's immune system is ready to attack foreign materials that show different antigens. BeforeBy giving transplantation, donors and graft recipients are checked for antigen compatibility to reduce the risk of graft refusal.
The most important of these antigens are human leukocyte antigens (HLA). These antigens are present on almost every cell in the body, but they get their name because white blood cells be carried by many of them. There are three main groups of HLA-HLA-A, HLA-B and HLA-DR. Each group contains many different antigens.
The voice is inherited, so you get half your HLA from your mother and the other half of your father. Related people tend to have very different HLA profiles, protrudes are the first compatibility tested when the patient needs transplantation. Blood writing must also be performed before the graft surgery. Some of the blood groups O, A, B and AB are incompatible with each other, so the donor patient must have a suitable blood type and a suitable HLA profile.
The immune system is refused if the antigen profiles do not match and immunosuppressive drugs do not do its job. Immunosuppressive drugs can be required for the rest of the life of the recipient of the tissue to prevent graft rejection. The graft refusal is diagnosed if the graft does not work properly or if the patient is sick or feels unusual discomfort. It is rarely manifested by rejection of graft in fever, pain or swelling.