What is the innate cytomegalovirus?
Congenital cytomegalovirus (CMV) is a condition that is found in newborns who have been infected with this virus in the womb. The greatest risk of developing this situation is when a mother who has not previously exposed to this virus is infected soon during her pregnancy. Although many infants are asymptomatic after CMV after exposure, some have severe manifestations, including low blood and malformated brain. The treatment of congenital cytomegalovirus infection focuses on the treatment of symptoms and the use of intravenous antivirus drugs.
Human cytomegalovirus is a pathogenic agent that infects many people around the world. It is commonly transmitted by contact with body fluids, including saliva and urine. As soon as the virus enters the body, it attacks the cells and replicates inside them. The virus can often remain in the human body for years after infection.
Problems may arise when a pregnant woman is first infected with CMV.Virus infects the mother, replicates in her cells and sends new viral particles to maternityBlood bed. These copies of CMV can pass through the placenta and enter the fetal circulation, causing infection in the developing child. The fetus usually has the worst infection if CMV is exposed at the beginning of the development process, especially in the first trimester of pregnancy.
The manifestations of congenital cytomegalovirus infections may vary, while some infants are asymptomatic and others have serious symptoms. Up to 90% of infants who had evidence of exposure to CMV before birth were initially asymptomatic and had no main problems. However, some of these children continued to problems with learning disabilities, mental retardation and hearing loss. These late development symptoms are often not associated with CMV due to their delayed presentation.
Other infants exposed to CMV in the uterus are born with serious symptoms of congenital cytomegalovirus. May have low birth weight, low number of red blood cells, jaundice,Reduced numbers of platelets in the blood and enlarged liver. Some also have congenital defects that change their physical appearance, including microcephaltes or a small head. These children with serious findings often have poor prognosis and have problems with mental retardation, seizures and engine development.
The treatment of congenital cytomegalovirus infection usually focuses on alleviating symptoms caused by diseases. For example, a child born with a low number of red blood cells can be treated with blood transfusion. Some scientists have investigated the benefits of treating infants with intravenous antiviral drugs and found that this therapy could help reduce the progression of some symptoms. For mothers who had CMV infection at the beginning of pregnancy by prenatal ultrasound caused serious congenital deformities, sometimes optional is offered. It has not been shown that treatment with antiviral substances during pregnancy offers no benefits.