What Is Epithelioid Hemangioendothelioma?

Epithelial hemangioendothelial cell tumor is also called histiocytoma hemangioma, which is a tumor between clinical and histologically between hemangiosarcoma and hemangioma, which can invade soft tissues and organs such as lung, liver, bone, etc. .

Basic Information

nickname: Histiocytic hemangioma
Visiting department: Cardiac Surgery
Multiple groups: Young men

Common locations: Upper or lower limbs
Common causes: still uncertain.
Common symptoms: Papules or nodules can be seen at the lesion.
Contagious: no

Causes of epithelioid hemangioendothelioma

The cause is unknown.

Clinical manifestations of epithelioid hemangioendothelioma

The disease is a multifocal vascular tumor that can invade soft tissues and organs such as the lungs, liver, and bones. Skin damage is rare, with single or multiple papules or nodules that slowly develop. Occurs in the upper or lower limbs, more common in men before the age of 25. Skin damage is often accompanied by bone involvement below it, with symptoms ranging from asymptomatic to severe burning pain.

Epithelial hemangioendothelioma

Histopathological examination showed two tissue structures of dilated blood vessels and spindle cells, and showed cell polymorphism and mitosis. Reticulin staining showed reticulated fibers surrounding individual cells and clusters of cells. Immunohistochemical examination was positive for factor 8-associated antigen and virgin hemagglutinin. Epithelial membrane antigen and cytokeratin staining are usually negative.