What Is Essential Fatty Acid Deficiency?

Essential fatty acids (EFA) include linoleic acid and arachidonic acid, which are omega-6 (n-6) fatty acids, and linolenic acid, ketotetraenoic acid, and carbodicarbonate, which are omega-3 (n-3) fatty acids. Enoic acid (see section 1). The body can synthesize arachidonic acid from linoleic acid, and synthesize docosa tetraenoic acid and docosapentaenoic acid from linolenic acid. Vegetable oils such as corn oil, cotton seed oil and soybean oil are Sources of oleic acid and linolenic acid; fish oil is a source of docosatetraenoic acid and docosapentaenoic acid. The amount of EFA required for adults is 1% to 2% of dietary energy and 3% for infants, and omega-6 is recommended : -3 fatty acid ratio is 10: 1.

Essential fatty acid deficiency

Essential overview of essential fatty acid deficiency

Essential fatty acids (EFA) include linoleic acid and arachidonic acid, which are omega-6 (n-6) fatty acids, and linolenic acid, ketotetraenoic acid, and carbodicarbonate, which are omega-3 (n-3) fatty acids. Enoic acid (see section 1). The body can synthesize arachidonic acid from linoleic acid, and synthesize docosa tetraenoic acid and docosapentaenoic acid from linolenic acid. Vegetable oils such as corn oil, cottonseed oil and soybean oil are Sources of oleic acid and linolenic acid; fish oil is a source of docosatetraenoic acid and docosapentaenoic acid. The amount of EFA required for adults is 1% to 2% of dietary energy and 3% for infants, and omega-6 is recommended : -3 fatty acid ratio is 10: 1.

EFA is required for many physiological processes, including maintaining the integrity of the skin and the structure of cell membranes, as well as the synthesis of prostaglandins and leukotrienes. Carbotetraenoic acid and docosapentaenoic acid are important components of the brain and retina.

Essential fatty acid deficiency symptoms

Term infants fed with skimmed milk formula with low linoleic acid content will experience growth retardation, thrombocytopenia, hair loss, and systemic scaly dermatitis, similar to congenital ichthyosis, and accompanied by increased water loss from the skin route.

Prevention and treatment of essential fatty acid deficiency

Supplementation with linoleic acid can improve the syndrome. Deficiency is unlikely to occur in a balanced diet, although the content of linoleic acid in cow's milk is about 25% of human milk. Although total fat intake is very low in many developing countries However, most of the fats taken are plant-derived and rich in linoleic acid and a certain amount of linolenic acid.

EFA deficiency has long been a danger of long-term fat-free parenteral nutrition, and fat emulsions are now commonly used to prevent this. For example, a 10% soybean oil emulsion contains 56g / L linoleic acid and 8g / L flax A case of linolenic acid deficiency, which was characterized by peripheral neuritis and blurred vision, occurred in a 6-year-old girl with short bowel syndrome. It contained 77g / L of linoleum for up to 9 months Lack of acid and linolenic acid with only 0.1 g / L of venous fat products resulted in nutritional deficiency. After supplementation with linolenic acid, symptoms and signs disappeared.

In the early stages of EFA deficiency, the levels of linolenic acid and arachidonic acid in the plasma are low, and there are 5,8,11-fluorenic acid that is an abnormal by-product of oleic acid desaturation metabolism. The normal upper limit for the ratio of carbotetraenoic acid (arachidonic acid) is 0.2. Evidence of EFA deficiency based on this ratio has been observed in patients with fat malabsorption, severe trauma, and burns.