What Is Fibrous Dysplasia?
Skull fibrous dysplasia of skull (fribrous dysplasia of skull), also known as skull fibrous dysplasia or skull fibrous structure, is a fibrous tissue that replaces bone and causes the skull to thicken and deform. The lesions involve the skull, but also bones in other parts of the body, such as femur, tibia, spine, etc. A few are accompanied by skin tan pigmentation and precocious puberty, known as McCune-Albright syndrome.
- nickname
- Skull Fibrous Dysplasia, Skull Fibrous Dysfunction
- Visiting department
- neurosurgery
- Multiple groups
- Teen women
- Common locations
- skull
- Common causes
- The etiology is unknown, mostly considered to be a scientific disorder; or it is considered to be related to inflammation or vascular, neurological, and endocrine dysfunction; or it is related to the abnormal growth of bone mesenchyme
- Common symptoms
- Slight headache, progressive vision loss or even blindness, bony lion face, conductive deafness, etc.
Basic Information
Causes of Skull Fibrous Dysplasia
- The etiology of this disease is unknown. Most people think that osteofibrosis is a genetic disorder, but some people think it is related to inflammation or dysfunction of blood vessels, nutritional nerves, endocrine, and others. Growth related.
Clinical manifestations of skull fibrous hyperplasia
- Skull fibrous dysplasia is more common in adolescents, but also in adults, and more common in women. All skulls can be affected, and clinically, most of the lesions invade the frontal and parietal bones, especially the base of the skull. Most patients are asymptomatic, and individual patients may experience mild headaches. The most common clinical manifestations are changes in the shape of the head and face and local asymmetric protrusions of the skull. The ridges are soft and hard, rubbery, and contain sand-like ossified islands.
Skull Fibrous Hyperplasia
- The mild or moderate elevation of alkaline phosphatase in the blood is of reference value in the diagnosis of cranial fibrous hyperplasia.
- X-ray examination has diagnostic value for skull fibrous hyperplasia. The plain radiographs of the skull are mainly round or quasi-circular light-transmitting areas within the cranial cover, and the skull base lesions are dense and thickened. Because normal bone is replaced by fibrous tissue, with bone hyperplasia and cartilage residue, its manifestations can be varied.
Diagnosis of Skull Fibrous Hyperplasia
- Diagnosis can be made based on clinical manifestations such as age and location of the onset, especially in combination with the characteristics of the skull X-ray manifestations.
Skull Fibrous Dysplasia Treatment
- The disease has a tendency to heal itself and can stop developing after puberty. Can try calcium and vitamin D treatment. The facial deformity can be severely removed to achieve cosmetic purposes.
- It is generally believed that the visual impairment caused by lesions is caused by the narrowing of the optic nerve forcing the optic nerve. Therefore, if the bone fibrous dysplasia syndrome is located in the orbit, early resection and decompression of the optic canal can effectively prevent vision loss, and the risk of neurological damage caused by surgery is not great. If visual impairment has already occurred, optic nerve decompression should be performed early.