What is a glomerular disease?

Glomerular disease concerns a group of disorders that attack units for kidney blood filtering, called glomeruli. Renal disorders that include glomeruli destruction fall into two categories. The first category is called glomerulonephritis and the second is called glomerulosclerosis. Both subgroups of glomerular diseases can cause irreversible kidney damage that can lead to the final kidney disease (ESRD).

Health conditions that cause glomeruli inflammation and related kidney structures are referred to as glomerulonephritis or glomerular nephritis. In glomerulonephritis, it damages acute and chronic glomeruli inflammation and important kidney structures. As a result, the kidneys will prevent the filtration of waste products, which will allow toxins to accumulate in the blood. Common symptoms of glomerulonephritis are foaming urine, blood in the urine and swelling or swelling.

autoimmune, hereditary conditions and certain infections can cause glomerular session to develop, specifically glomerulonEfritis. System lupus erythematosus (SLE), GoodPasture syndrome and immunoglobulin and (IgA) nephropathy are usually the most common autoimmune conditions that affect the kidneys. In each of the above autoimmune disorders, the body creates harmful autoantibodies that are stored in the glomerulus, causing inflammation. Finally, glomeruli inflammation usually leads to scarring and reducing kidney function.

Alport syndrome is a hereditary condition that can cause chronic glomerular disease. In general, men with syndrome are more likely to damage kidneys than women. Unlike Alport's syndrome, anyone can develop a bacterial infection that leads to kidney disease. Bacterial infections such as acute post-streptococcal glomerulonephritis (PSGN) may develop after episode of the neck or impetigo. Like autoimmune disorders, PSGN damages the kidneys by stimulating too muchEmune system for the production of antibodies that are eventually stored in the glomeruli.

 

in glomerulosclerosis, glomeruli and surrounding structures in the kidneys solidify and scar. Once scarring occurs, the kidney damage is irreversible. As a result, the scarring of the glomeruli causes disturbance of the kidney filtering process. The condition usually proceeds until the patient experiences ESRD. Symptoms such as proteinuria, which is excessive protein secretion, are usually not present until after a glomerular disease significantly proceeded.

 

glomerulosclerosis is usually caused by sclerotic diseases such as diabetes. Uncontrolled diabetes is characterized by increased blood glucose. Over time, patients with uncontrolled diabetes are more than likely to develop kidney nephropathy. Diabetic induced nephropathy damages the kidneys by scarring and stressful blood vessels in the kidneys. The rate of progression in diabetic nephropathy may be minimized by blood glucose levels and blood reductionlacquer.