What is immunoglobulin e?

Immunoglobulin E (IgE) is a protein called an antibody that is produced by cells in the body known as lymphocytes. IgE primarily contributes to an allergic reaction. Some patients may respond to various allergens such as pollen, medicines or food. When the patient encounters allergen, IgE binds to cells known as mast cells. These galloping cells are activated to release histamine granules, which then create symptoms of allergic response. These B-cells exclude different types of antibodies or immunoglobulins and are part of a humoral immune response. When the patient is first exposed to allergen, some of these B-cells are activated and begin to secrete immunoglobulin E. This GE binds to the surface of the mast cells present in the body tissues. It can also be bound to other cells in the blood called basophily.Sitized, but there was no allergic reaction. At the time of the second exhibition, the allergen is bound to the molecules of immunoglobulin E on the cell surface. IgE molecules then connect to each other with an allergen that signals a cellKy to release granules containing histamine, enzymes or other proteins known as cytokines.

This IgE response is very strong and can start within two to 30 minutes after exposing the allergen. The release of histamine or other proteins can irritate the mucous membranes, cause blood vessels to dilate or cause smooth respiratory muscles to restrict. Symptoms for the patient may range from sneezing and hay fever to life -threatening symptoms of anaphylactic shock.

Identification of the substance producing the response of immunoglobulin E is the first step in treatment. The patient may already know what triggers the answer. If not, medical you want to use a skin test for diagnosis. The skin is placed extracts of pollen, dust, food or drugs, followed by a small needle. If the patient is allergic to one of the substances, a small inflamed area is developing at this point.

Allergies treatment begins with the PatiaNTA avoids the cause of the reaction. Most food allergens or drugs can be prevented. In patients with mild symptoms of hay fever, the drug may alleviate symptoms against historinics. Antihistamins do not prevent immunoglobulin e response, but rather block the effect of histamine as soon as it is released from the granules.

If the allergen is in the air or the contact cannot be controlled, as with bee stings, the patient may have immunotherapy. Injections of very small doses of allergens are administered under the skin to sensitize the patient and control the answer. These injections are usually given twice a week for several months.