What Is Immunoglobulin E?

B lymphocytes are transformed into plasma cells under the stimulation of antigens, producing antibodies that can specifically bind to the corresponding antigens, called immunoglobulins. Immunoglobulin E (IgE) has a high affinity for basophils and mast cells, so it is also called reactin or cytophilic antibody. IgE is mainly produced by plasma cells in the lamina propria of the respiratory tract and digestive tract, which is extremely low in normal human blood, accounting for about 0.002% of total serum Ig. IgE is related to type I allergies. In patients with allergies or hypersensitivity, the serum IgE is significantly higher than that of normal people. Therefore, the content of IgE in the serum is too high, which often indicates the existence of genetic allergy or type I allergies.