What is hepatitis lupoid?
lupid hepatitis, commonly known as autoimmune hepatitis (AIH), is a disease in which the immune system attacks liver cells and causes inflammation. The term "lupoid" refers to the previous connection with those who had an autoimmune disease known as systemic lupus erythematosus (SLE). Patients SLE may still have lupid hepatitis, but many other cases have been found in other autoimmune disorders, the term lupid hepatitis has fallen out of favor. In some cases, it may proceed and cause lesions and scarring of the liver, which is known as cirrhosis. It is most common in women and is considered a chronic disease. A large percentage of those with type 1 also has other autoimmune diseases such as Graves' disease or type 1 diabetes. Type 2 is less common and occurs in children, mostly women, aged 2-14 years. It is more serious and more often proceeds to cirrhosis of the liver than type 1.
Symptoms of LupoIdent hepatitis may vary depending on the severity and stage of the disease. People in earlier stages have little symptoms. If symptoms occur, fatigue is usually the first feature. Other symptoms include abdominal discomfort, itching and joint pain. It makes the skin and white eye yellowing, can also be seen.
In multiple progressed cases, nausea and vomiting, along with enlarged liver, may be symptoms. Blood vessels, called angioms, sometimes appear on the abdominal area of the skin. Many symptoms may resemble viral hepatitis, so it is important to check any type of viral symptoms.
diagnosis for lupid hepatitis is made either by blood work, which also helps to exclude other forms of hepatitis or liver biopsy. In lupid hepatatis type 1, antibodies of antinuclear antibodies (ANA) and smooth muscle antibodies (SMA) are present, either separately or together; Type 2 are present anti-klm (AKLM), antibodies against liver and kidney microzomes.
nThe more -running form of treatment in the early and medium stages of the disease is prednisone, corticosteroid that suppresses the immune system and reduces inflammation. Since prednisone has side effects, the dosage is carefully monitored and gradually narrows down to a lower dose. Other medicines are also used to suppress the immune system. In more severe cases, liver transplantation will be performed.
The prognosis for lupid hepatitis depends on several factors, especially when it comes to another disease, but is generally good. It must often be treated for at least 6 months to return the results of liver blood tests to normal, even if it can take longer. Sometimes it must be treated and for for life. In very mild cases, no treatment may be prescribed.