What is lymphomatoid granulomatosis?

Rare neoplastic disease, lymphaidoid granulomatosis, usually develops in certain white blood cells contained in the blood and lymphatic systems. Abnormal cells proliferate above normal levels and circulate throughout the body, accumulate in blood vessels and various body tissues. These diseases create a number of symptoms depending on the location of abnormal cell aggregation. Cell destruction caused by lymphoproliferative disorder generally leads to death over five years, but some patients experience remission after treatment.

The disorder primarily affects B cells of the immune system that normally produce antibodies against organisms perceived as a threat. Scientists believe that the Epstein-Barr virus may be responsible for lymphomatoid granulomatosis cancer because tissue samples usually reveal the presence of these viral cells. Because the disease affects the production and development of B cells, the scientists are the affliction is similar to Neckkin's lymphoma. Abnormal cells can gatherRotate anywhere in the body and create symptoms specific to a particular organ or system, but are often stored in the central nervous system, lungs and skin.

patients usually experience fever and weight loss accompanied by a general feeling of illness. When the disorder infiltrates the lungs, they may have difficulty breathing and the feeling of secrecy of the chest. Colored mucus and productive cough are generally symptoms of secondary infection or bleeding of cells and death often occurs due to respiratory failure. Lymphomatoid granulomatosis can also produce skin conditions related to lymphoid causing painful, raised and reddish areas on the skin. In addition, skin conditions may include subsurface nodes that are eventually ulcked.

If the lymphomatoid granulomatosisinfilt is the central nervous system, the disease affects blood vessels, brain and nerve tissue. There is inflammation and patients usually develop menIngitis with symptoms that include behavior, cognitive or sensory changes, seizures, paralysis or lack of physical coordination. When abnormal cells collect in a sufficient number of blood vessels, patients usually experience hypertension and as the pressure on the vascular walls increases, the condition generally destroys blood vessels, resulting in bleeding.

This disease usually develops more often in men, in persons over 50 years of age and in persons who have a weakened immune system. Healthcare providers generally diagnose lymphanoid granulomatosis by scanning computer tomography, displaying magnetic resonance imaging and tissue biopsy. Depending on the stage of the disease process, doctors can use corticosteroids to reduce inflammation along with chemotherapy, radiation and surgery. Transpl bone marrow treatment can also be implemented by ants, antiviral drugs or interferon therapy.