What Is Paraneoplastic Pemphigus?

The researchers cultured tumor cells in vitro, and analysis of the cultured cell supernatant showed that B cells in the tumor can secrete antibodies. Then, the research group carried out research from the perspective of immunogenetics. The study on the highly variable region genes of B-cell immunoglobulin heavy chains in tumors showed that the gene sequences are very similar in different patients and have the basis for secreting the same specific antibodies.