What is Supination?
The isomerization of atoms or groups of atoms in asymmetric molecules with different effects on the plane of polarization of plane polarized light is called optical isomerism, and the isomers it produces are called optical rotation Isomers (optical antipodes).
- Two or more molecules exhibit different optical rotation properties due to differences in configuration. These molecules are each other
- Classification of isomerism
- Molecular isomerism can be divided into two categories: structural isomerism and stereoisomerism. Structural isomerism can be divided into carbon chain isomerism, positional isomerism and functional group isomerism; stereoisomerism can be divided into configurational isomerism and conformational isomerism; among them, configurational isomerism can be divided into cis-trans isomerism Geometrical isomerism) and enantiomers (optical isomerism) .
- Molecular chirality
- When one carbon atom in the molecule is connected to four different groups, the compound may have two different arrangements.
- The causes of optical isomerism can be classified according to the types of optical isomers. There are three types:
- The molecule contains a chiral carbon atom
- Contains one
- Investigate organic chemical reaction processes
- Stereochemistry in the reaction
- By analyzing and comparing the optical rotation properties in the product results, the ratio of the racemate can be analyzed to obtain the reaction process. [3]
- Applications of chiral molecules
- Significance of obtaining chiral molecules-the relationship between drugs and humans: most of the biological macromolecules that constitute living systems exist in an enantiomeric form. Therefore, the drug and its effect are also carried out in a chiral manner, and the enzymes and cell surface receptors of the organism are chiral, so the processes of recognition, digestion and degradation of racemic drugs are also different. Source of chiral molecules in nature: asymmetric organic synthesis of sugars, amino acids, biodegraders, terpenes, and steroids. [4]