What is agammaglobulinemia associated with X?
X-bound agammaglobulinemia is a rare genetic disorder that affects the immune system, which makes it difficult to fight infection. Many different names such as Hypogammaglobulinemia are assigned to X, agammaglobulin -type bruton, Bruton syndrome and agammaglobulinemia associated with sex. The shortened name of the fault is XLA. It is only found in X-chromosome, which only occur in men. These antibodies are the main defensive line of the body against bacteria, viruses and other forms of infection or disease. This happens because people with XLA cannot create mature B-lymphocytes, which are cells that create antibodies found in the blood. The disorder is usually discovered in men during the first two years of their lives, because they constantly become ill with infections that their bodies should be able to fight. Many times it requires serious conditions such as meningitis, sepsis or pneumonia for diagnosis of x-bound agammaglobulinemia.
In addition to repeated infections, there are other symptoms of agammaglobulinemia associated with X. These include lack of almonds and adenoids, stunted growth, joint diseases and kidney and muscle inflammation. Since many of these symptoms are also symptoms of other, more frequent, disorders and diseases, XLA diagnosis may not be obvious immediately. However, the sooner the disease is identified in the child, the better. Uniagnosed or untreated cases of agammaglobulinemia associated with X almost always end in death on infection.
As soon as the diagnosis of x-bound agammaglobulinemia is made, treatment may start that can handle the disorder. This usually includes the use of gammaglobulin antibodies through an injection or infusion every two to four weeks. Because the disorder will never disappear, this treatment must continue for the rest of the life of a person.
In addition to planned injections, Men with XLA will often use antibiotics to help fight any infections that can occur before ST stAnk life threatening. Even in injections and regular medicines, XLA side effects are common and can be weakening. Including chronic lung disease and sinusitis; bowel disease and recurring enterovirus infections. Each of these side effects is usually treated with other antibiotics. If they are caught early and regularly treated, people with X-bound agammaglobulinemia can usually lead normal lives.