What are the different interactions of clarithromycin?

Clarithromycin is a general name for oral antibacterial drugs to the market called biaxin®. The common use of clarithromycin is the treatment of certain ulcers, legionnaires and infections caused by bacteria. Other medicines, food and existing conditions can interact with drugs. Some of these interactions are mild, but others may be life -threatening. One of the greatest risks of clarithromycin is interaction with drugs such as blood thinners, heart drugs, statins, reliefs of pain and sedatives, as well as certain drugs for erectile dysfunction or seizures.

Many drugs that are safe at normal doses can become toxic if combined with clarithromycin. Antibacterial affects how well they process liver toxins and this decrease in hepatic function can lead to dangerous accumulation of drugs in the body. Clarithromycin interactions were reported with carbamazepine, chlorineazepoxide, diazepam, colchicin and ergothemers based on migraine drugs.

Claromycin interaction is also possible when antibacterial use of drugs used to regulate heart rhythm such as digoxin. The reason is that clarithromycin can change the rhythm itself. Combined with other medicines, which also change heart rate, a potentially serious condition known as the extension of QT may occur. Patients taking digoxin or similar drugs are exposed to the greatest risk of clarithromycin interactions that affect the cardiovascular system. Since patients with low potassium or magnesium levels have an increased risk of QT extension, patients who have exhausted the level or use diuretics that can reduce these levels, should discuss the use of claritromycin with their doctors.

One of the potential side effects of blood thinners, such as warfarin, is an increased risk of bruises and bleeding. Clarithromycin can cause blood too much to thin. Were reported nosebleesBut cases of internal bleeding have also been reported, some of which were quite serious.

potentially serious clarithromycin interactions have also been reported in patients who used theophylline, pimoside, ranitidine, terpenadine, vardenafil, nevirapin and Atazanavir. Some reports of disturbed thinking and sleep disorders were attributed to the interaction with the triazolam. Other medicines such as ITRACONazole and Saquinavir have resulted in two -way interactions of clarithromycin, which affect the effectiveness of both drugs.

Patients with liver or kidney disease should be carefully monitored if their doctors decide to prescribe clarithromycin, as antibacterial can reduce the ability of these organs to remove toxins. Particular attention must be paid to those who have a deteriorated function of kidney or liver if they take any drugs to protect against claritromycin interactions. Doctors are usually reluctant to prescribe clarithromycin patients with myasthenia gravis, which is a disorder that causee muscle weakness.