What factors affect the dosing flagyl?
Generic metronidazole drug, sold under the Flagyl® brand, is an antibiotic considered to be a specific treatment of trichomoniasis, amoebiasis and anaerobic bacterial infection. Standard dose adjustments according to age, condition, duration of treatment, reproductive condition, liver health and the level of kidney function must be made. Due to the considerable dispersion between patients in drug pharmacokinetics, the individual dose of Flagyl® must be adapted to each patient's reaction. In particular, the level of the drug in the older patient's drug may be required to determine whether to modify their dosing Flagyl®.
When the drug is used to treat patients suffering from trichomoniasis, it can be administered in one or seven -day course of treatment. Although there is some evidence that seven -day treatment may have a higher success rate, shorter exchange rate compliance ensures that the patient is administered if he is supervised and reduces the risk of further resistance to the drug. Patients receiving a drug for seven days should be givenKA FLAGYL® 250 mg three times a day at all times. Patients receiving a drug for one day can receive 2 g Flagyl® in one dose or in two 1 g doses extended during the day. It is also important that some potentially infected sexual partners also receive treatment to avoid reinfection.
Due to the risks of drugs, the following treatment courses should not undergo four to six weeks of the end of the previous treatment. Total and differential white blood cells of the patient should be monitored before and after repeated courses. If laboratory results are negative to trichomoniasis or if the patient is in the first one should be used trimester of pregnancy, alternative treatment. In pregnant patients where alternative treatment was ineffective, seven -day treatment should be followed, as higher one -day Flagyl® may exceed the fetal blood supply.
When Flagyl® is used PThe treatment of adult patients with acute amoebic infections such as amoebic consideration should be administered 750 mg of drug for five to ten days three times a day. Adult patients suffering from amoebic liver abscesses can receive Flagyl® dosing between 500 and 750 mg three times a day for the same time. In the treatment of pediatric cases of amoebiasis, the relevant dose of Flagyl® is between 35 and 50 mg to £ 2.2 (1 kg) of body weight, administered in three divided doses for ten days.
The drug is also used in the treatment of serious anaerobic bacterial infections. After closing the intravenous handling of the flag, the drug is usually given orally for at least seven to ten days. The typical recommended Flagyl® for adults is 7.5 mg at 2.2 pounds (1 kg) of body weight every six hours, although more than 4 g should not be administered within 24 hours.
Regardless of the condition, patients with reduced liver function should receive lower Flaggyl® doses, as well as patients with reduced kidney function.These patients should have monitored plasma drug levels to ensure that the dosage is correct. However, patients undergoing dialysis may not require dosing, as Flagyl® is quickly removed.