What is bioequival?

Bioequivalence is standard generic drugs to be met before they are released on the market. When the drugs are bioequivalent, they are considered functionally the same. The brand and general should have the same effects with very small variations. When companies prepare generic drugs for release, medicines are reviewed on the bioequival by a regulatory agency and, like branded drugs, can later be pulled out of the market if they are dangerous, or if further research shows that it is not really organic. to. It can be harder than it sounds. Two drugs with the same active ingredient may be absorbed differently, depending on the inactive ingredients involved in their production. The use of various coatings, cartridges and other ingredients can change the way in which it is absorbed and all these details must be tuned before the drug entry.

For convenience, the bioeekvivalent drugs must be packed inthe same formats and doses. For example, if a medicine is available in oral tablets, oral tablets will be used to create the bioeekvivalent version and the available sizes will be identical. This is designed to ensure that the recipes can be easily confused without the risk for the patient. If the patient is prescribed five milligram tablets to be taken twice a day, any bioequivalent drugs can be used to fill the regulation.

When the standard of bioequival is met, it means that the general formulation is as safe and efficient as the brand. It has the same way on the body and can be used interchangeably and identical. However, there may be small changes between drugs due to inactive ingredients. One can use corn starch as a filler, for example, potentially pose a risk of allergy, while others do not. Knowing about these differences is important for people with allergies, because it must ensure that when the drug is prescribed, they receive them in a safe format.

If testing forIt spares that the drug is not bioeverivalent, will have to be re -re -formulated and tested on the bioequival. This can be expensive and, if possible, this is prevented by careful steps during development and timely testing. The bioequivalent generic drugs are cheaper than the formulation of the brand, because their manufacturers do not have to invest in clinical evaluation to test the safety and efficacy of the active ingredient as it has already happened.