What is chlorquin?
Chloroquine is a medicine that is extensively used to prevent and treat malaria. It is still effective in some parts of the world. In most of the world, however, the parasites have developed resistance that causes malaria, especially against the main tribe. Other medicines are now often used to treat this disease. Cloroquin also has some mild anti -anti -anti -anti -product and is used as an anti -treumatic product. This is due to several different types of parasites in the family plasmodium . These parasites live in red blood cells (RBC) and generally spread from one person to the other by bite of infected mosquitoes. It will do this to obtain amino acids that are building blocks of proteins. One complication of this strategy is that hemoglobin contains a heme-duster-containing compound that binds oxygen-which can be toxic in large quantities. The parasite concentrates HEME in crystals, in a specialized cellular compartment called a vacuol, where it does not disturb cellular metabolism. In the vacuole, it is captured and reacted with Hemu crystals. In thatThis form cannot add any other heme molecules. HEME then creates toxic concentration and baking parasite.
This anti -malarial agent has been widely used for decades, despite its initial concern for its toxicity for people. Resistance has been built on this medicine, especially with the Plasmodium Falciparum , the causal agent of the most dangerous forms of malaria. Several resistance mechanisms seem to be known, but it is known that resistant forms of parasite are very effective in transporting chlorochin from cells.
Most cases of death on malaria occur in Sub -Saharan Africa. There is resistance to malaria endemic. Chlorochin can be used in parts of the world where drug resistance has not yet been confirmed. This includes the Caribbean, Central America and parts of the Middle East.
chloroquin can be very effective if administered as part of a small prevention campaignRII, for a suitable area. Travelers are asked to take it for about one to two weeks before traveling to the region where malaria is endemic. Then, for the duration of the journey and for four weeks for a period of time. The treatment of existing disease is usually performed at higher doses several times a day. There are certain measures in terms of its adoption, because this drug can be quite toxic.
patients should have their eyes regularly examined when taking chlorochin. Although blurry vision is common, medicines can be toxic to the eyes and even cause blindness, although it is most often just a problem with chronic use. Some people suffer from itching, which is sometimes serious enough to interrupt treatment.
Gastrointestinal disturbance is a common side effect and if the drug is taken with food, it is reduced. Cimetidine deteriorates the effects of chlorochine, maybe to toxicity, so you need to avoid. Patients should consult a doctor for any medicine for safetyH or herbal supplements in conjunction with this antimalarage agent.