What Is Ethyl Acetoacetate?
Ethyl acetoacetate is an important raw material for organic synthesis. It is used in medicine to synthesize aminopyroline and vitamin B. It is also used in the preparation of azo yellow dyes. It is also used to blend apple flavor and other fruit flavors. Intermediate -chloroacetoacetate, intermediate of pyrimidophos, the fungicide oxacillin, the herbicide azamethoxine, and the rodenticide The rodenticides, rodentin, etc., are also intermediates of the new fungicides azoxystrobin, fluoxastrobin, furazolid, and the plant growth regulator, androst, and ethyl acetoacetate is also widely used. Used in pharmaceutical, plastic, dye, perfume, varnish and additive industries.
- Widely used in the preparation of strawberry, apple, apricot, cherry, peach and other fruit and wine types (rum, whiskey, etc.)
Overview of the dangers of ethyl acetoacetate
- Health hazards: Irritating to skin. Harmful by inhalation, ingestion or absorption through the skin. Irritating to eyes, mucous membranes and upper respiratory tract.
- Explosion hazard: Flammable and irritating. [4]
Ethyl acetoacetate protection
- Engineering control: Closed operation, pay attention to ventilation.
- Respiratory protection: When the concentration in the air exceeds the standard, you must wear a self-absorption filtering gas mask (half-mask). Wear an air respirator for emergencies or evacuation.
- Eye protection: Wear chemical safety goggles.
- Body protection: Wear protective work clothes.
- Hand protection: Wear rubber oil resistant gloves.
- Other protection: Smoking is strictly prohibited at the work site. After work, take a shower. Pay particular attention to eye and respiratory protection. [4]
First aid measures for ethyl acetoacetate
- Skin contact: Remove contaminated clothing and rinse with running water.
- Eye contact: Raise eyelids and rinse with running water or saline. Seek medical attention.
- Inhalation: Remove to fresh air. If breathing is difficult, give oxygen. Seek medical attention.
- Ingestion: Drink plenty of warm water and induce vomiting. Seek medical attention. [4]
Ethyl acetoacetate fire protection measures
- Hazardous combustion products: carbon monoxide, carbon dioxide.
- Fire fighting methods: Firefighters must wear gas masks and full-body firefighting suits to extinguish fire in the upwind direction. Move the container from the fire to the open space as much as possible. Spray water to keep the fire container cool until the fire is over. Containers in the fire area must be evacuated immediately if they have discolored or generate sound from a safety pressure relief device. Spray the escaped liquid with water to dilute it into a non-combustible mixture and protect firefighters with mist water. [4]
- Fire extinguishing agent: water, mist water, solvent-resistant foam, dry powder, carbon dioxide, sand. [4]
Emergency treatment of ethyl acetoacetate leakage
- Emergency treatment: Quickly evacuate personnel from the leaked contaminated area to a safe area and isolate them to strictly restrict access. Cut off the fire. It is recommended that emergency handlers wear self-contained positive-pressure respirators and wear protective clothing. Cut off the source of the leak if possible. Prevent from flowing into restricted spaces such as sewers and flood drains. [4]
- Small leaks: Absorb with sand, vermiculite or other inert materials. It can also be rinsed with a large amount of water and diluted into the waste water system. [4]
- Large spills: build dikes or dig pits for containment. Cool with damp ice or ice water. Transfer to a tanker or special collector with a pump and recycle or transport it to a waste disposal site for disposal. [4]
Handling and storage of ethyl acetoacetate
- Precautions for operation: Closed operation, pay attention to ventilation. Operators must be specially trained and strictly abide by the operating procedures. It is recommended that operators wear self-absorbent filter-type gas masks (half-masks), chemical safety protective glasses, anti-poison infiltration work clothes, and rubber oil-resistant gloves. Away from fire and heat sources, smoking is strictly prohibited in the workplace. Use explosion-proof ventilation systems and equipment. Prevent vapors from leaking into the workplace air. Avoid contact with oxidants, reducing agents, acids and alkalis. Handle with care when handling to prevent damage to packaging and containers. Equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. Empty containers may be harmful residues. [4]
- Storage precautions: Store in a cool, ventilated warehouse. Keep away from fire and heat sources. It should be stored separately from oxidants, reducing agents, acids, and alkalis. Equipped with the appropriate variety and quantity of fire equipment. The storage area should be equipped with spill emergency treatment equipment and suitable containment materials. [4]