What are the different types of fatty oxidation disorders?
Disorders of oxidation oxidation (FOD) prevent the person from properly obtaining energy from fat. It is a genetic disorder that can lead to a number of very serious health problems. There are a number of different types of this disorder, including the lack of acyl-coa dehydrogenase in the middle chain (MCAD), very acyl-coaa dehydrogenases with long chain (VLCAD) and trifunction protein (TFP). Without treatment, oxidation disorders may cause seizures, brain damage and severe respiratory stress. Episodes of coma and heart arrest can even cause death. Although oxidation is genetic oxidation, the parent may only be a carrier for this group and may be aware of the possibility to pass it on to the offspring. However, it takes two genes to disorders of oxidation oxidation, which means that each parent must go through the child gene to affect the child. If only one parent passes through the gene and the other does not, the child will also be a carrier, but the symptoms of the disorder will not be affected.
MCAD occurs as a result of the missing enzyme. Individuals with MCAD will show symptoms in childhood and early childhood, although some are not officially diagnosed later in their lives. Symptoms include fatigue, loss of appetite, sudden onset of ear infection, vomiting or sudden onset of symptoms of colds or flu after it seemed completely healthy. If it is not detected in childhood, MCAD is sometimes poorly diagnosed and can be fatal if it is not recognized soon enough. Historically, doctors did not largely did not know about the presence of MCAD, but many children are now commonly tested for this disorder of oxidation oxidation immediately after delivery.
as MCAD, TFP will present similar oily oxagers disorders dated in infancy or early childhood. Other symptoms may include lack of response to infant pain, irritability, nitrous skin, muscle weakness and walking delay. WhileChildren with these disorders can rely on glucose for permanent energy, loss of appetite in children with feed can bring the blood sugar levels dangerously low and trigger an episode of mild to severe symptoms.
In Vlcad, symptoms occur with decreasing blood sugar. As a result of this decline, long chain fatty acids do not decompose, which leads to too many of them present in the body. This overpopulation can cause weakening and enlargement of the heart muscles. These symptoms create a chain reaction by also interrupting the rhythm of the heart and causing damage to other vital organs such as the kidney and the liver, which are completely dependent on the optimal blood circulation for functioning.