What Is a Panel Reactive Antibody?

Population-reactive antibody (PRA) is a group of specific HLA-reactive antibodies, and it is an important indicator for screening allergic recipients before various tissue and organ transplantation. Detecting the level of reactive antibody in the recipient population can determine the sensitivity of the recipient's serum during organ transplantation. Those with high serum sensitization are prone to hyperacute rejection. For such patients, plasma exchange, immunoadsorption and induction of immune tolerance can be performed first. Wait to reduce HLA antibodies in body fluids and improve graft survival.