What Is an Antigenic Shift?

The mutation range is large, and the mutation rate of HA amino acids is 20% -50%, which leads to the emergence of new subtypes. The mechanism is mainly gene reassortment between two different types of influenza viruses.

Antigen switching

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The mutation range is large, and the mutation rate of HA amino acids is 20% -50%, which leads to the emergence of new subtypes. The mechanism is mainly gene reassortment between two different types of influenza viruses.